2021
Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates
Fuery MA, Chouairi F, Natov P, Bhinder J, Rose Chiravuri M, Wilson L, Clark KA, Reinhardt SW, Mullan C, Miller PE, Davis RP, Rogers JG, Patel CB, Sen S, Geirsson A, Anwer M, Desai N, Ahmad T. Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates. Journal Of The American Heart Association 2021, 10: e023662. PMID: 34743559, PMCID: PMC9075266, DOI: 10.1161/jaha.121.023662.Peer-Reviewed Original ResearchConceptsLow-urgency patientsHigh-urgency patientsUrgency patientsCardiac transplantationAllocation system changeLonger waitlist timesOrgan Sharing databaseTime of transplantationCardiac transplantation candidatesNew allocation systemBaseline recipientPosttransplantation outcomesPosttransplantation survivalAdditional comorbiditiesClinical characteristicsConclusions PatientsHepatitis CIschemic timeTransplantation candidatesSharing databaseWaitlist timeWaitlist survivalUnited NetworkRetrospective analysisPatients
2015
Cardiac dysfunction associated with a nucleotide polymerase inhibitor for treatment of hepatitis C
Ahmad T, Yin P, Saffitz J, Pockros PJ, Lalezari J, Shiffman M, Freilich B, Zamparo J, Brown K, Dimitrova D, Kumar M, Manion D, Heath-Chiozzi M, Wolf R, Hughes E, Muir AJ, Hernandez AF. Cardiac dysfunction associated with a nucleotide polymerase inhibitor for treatment of hepatitis C. Hepatology 2015, 62: 409-416. PMID: 25251156, DOI: 10.1002/hep.27488.Peer-Reviewed Original ResearchConceptsNucleotide polymerase inhibitorLVEF dysfunctionPolymerase inhibitorsB-type natriuretic peptide levelsChronic hepatitis C virus (HCV) infectionHepatitis C virus infectionActing antiviral (DAA) agentsSevere myocyte damageC virus infectionNatriuretic peptide levelsPhase II studyVentricular ejection fractionT-wave inversionOff-target toxicityHCV treatmentHepatitis CII studySystolic functionTransthoracic echocardiogramEjection fractionNew DAAsCardiac dysfunctionElectrocardiogram changesPathological findingsCardiac toxicity