2022
Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s disease
Cherry J, Kamel S, Elfil M, Aravala S, Bayoumi A, Patel A, Sinha R, Tinaz S. Mental imagery content is associated with disease severity and specific brain functional connectivity changes in patients with Parkinson’s disease. Brain Imaging And Behavior 2022, 17: 161-171. PMID: 36434490, PMCID: PMC10050121, DOI: 10.1007/s11682-022-00749-z.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingHumansImaginationMagnetic Resonance ImagingParkinson DiseasePatient AcuityConceptsImagery trainingFunctional connectivity changesMild Parkinson's diseaseVisual imagery trainingMental imagery trainingComplex cognitive processesConnectivity changesMotor imagery trainingBrain functional connectivity changesFunctional connectivity characteristicsExecutive processesMental imageryCognitive processesPerceptual experienceNeural correlatesBrain mechanismsImagery practiceImagery contentSensorimotor processesNeuropsychiatric patient populationsMotor functionMotor actsMotor enhancementBrain areasParkinson's disease
2015
Deficits in task-set maintenance and execution networks in Parkinson’s disease
Tinaz S, Lauro P, Hallett M, Horovitz SG. Deficits in task-set maintenance and execution networks in Parkinson’s disease. Brain Structure And Function 2015, 221: 1413-1425. PMID: 25567420, PMCID: PMC5565229, DOI: 10.1007/s00429-014-0981-8.Peer-Reviewed Original Research
2014
Role of the sensorimotor cortex in tourette syndrome using multimodal imaging
Tinaz S, Belluscio BA, Malone P, van der Veen J, Hallett M, Horovitz SG. Role of the sensorimotor cortex in tourette syndrome using multimodal imaging. Human Brain Mapping 2014, 35: 5834-5846. PMID: 25044024, PMCID: PMC4776755, DOI: 10.1002/hbm.22588.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidSensorimotor cortexTourette syndromeFunctional magnetic resonance imagingBeta band powerH-Magnetic Resonance SpectroscopyState functional connectivity patternsMagnetic resonance imagingFunctional connectivity patternsMost patientsProcessing disturbancesSensory processing disturbanceVocal ticsLimbic inputsMotor phenomenaPremonitory sensationsPatientsResonance imagingTic generationNeuropsychiatric disordersAnterior insulaBand powerBeta oscillationsBeta activitySyndrome
2010
Focal cortical and subcortical atrophy in early Parkinson's disease
Tinaz S, Courtney MG, Stern CE. Focal cortical and subcortical atrophy in early Parkinson's disease. Movement Disorders 2010, 26: 436-441. PMID: 21462259, PMCID: PMC4502575, DOI: 10.1002/mds.23453.Peer-Reviewed Original ResearchConceptsParkinson's disease patientsDisease patientsParkinson's diseaseDisease groupEarly-stage Parkinson's disease patientsSubstantia nigra pars compactaAnxiety state scoresFocal cortical thinningEarly Parkinson's diseaseParkinson's disease groupCortical thickness changesManifest Parkinson's diseaseStriatal volume lossSubcortical structural changesOccipito-parietal areasHealthy control participantsLimbic cortexPars compactaSubcortical atrophyCortical thinningVentrolateral prefrontal cortexCortical thicknessSubcortical volumesControl groupAlzheimer's disease
2005
Evidence for the importance of basal ganglia output nuclei in semantic event sequencing: An fMRI study
Tinaz S, Schendan HE, Schon K, Stern CE. Evidence for the importance of basal ganglia output nuclei in semantic event sequencing: An fMRI study. Brain Research 2005, 1067: 239-249. PMID: 16360121, DOI: 10.1016/j.brainres.2005.10.057.Peer-Reviewed Original ResearchConceptsPicture sequencing taskSequencing taskBasal ganglia output nucleiEvent sequencingHigh-level cognitive functionsFrontal lobeDorsolateral prefrontal cortexSequential orderingOutput nucleiNeural representationDiscrimination taskFMRI studyPicture sequencingPrefrontal cortexCognitive functionNeural systemsControl taskSelective updatingMeaningful eventsTaskSignificant activationKey computationRandom orderTemporal relationshipFMRI