2000
Chronic graft‐versus‐host disease of the liver: Presentation as an acute hepatitis
Strasser S, Shulman H, Flowers M, Reddy R, Margolis D, Prumbaum M, Seropian S, McDonald G. Chronic graft‐versus‐host disease of the liver: Presentation as an acute hepatitis. Hepatology 2000, 32: 1265-1271. PMID: 11093733, DOI: 10.1053/jhep.2000.20067.Peer-Reviewed Original ResearchConceptsSmall bile ductsBile ductChronic graftHost diseaseAcute hepatitisLiver dysfunctionAlanine transaminaseHigh-dose immunosuppressive therapyProgressive bile duct destructionAllogeneic hematopoietic cell transplantationBile duct destructionChronic liver GVHDHigh-dose immunosuppressionAcute viral hepatitisHematopoietic cell transplantationSerum alanine transaminaseCholestatic pictureChronic GVHDEye involvementImmunosuppressive medicationsLiver GVHDLobular hepatitisMedian bilirubinNecroinflammatory fociDuct destruction
1999
Use of rituximab and irradiated donor-derived lymphocytes to control Epstein–Barr virus-associated lymphoproliferation in patients undergoing related haplo-identical stem cell transplantation
McGuirk J, Seropian S, Howe G, Smith B, Stoddart L, Cooper D. Use of rituximab and irradiated donor-derived lymphocytes to control Epstein–Barr virus-associated lymphoproliferation in patients undergoing related haplo-identical stem cell transplantation. Bone Marrow Transplantation 1999, 24: 1253-1258. PMID: 10642818, DOI: 10.1038/sj.bmt.1702052.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntibodies, MonoclonalAntibodies, Monoclonal, Murine-DerivedAntigens, ViralAntineoplastic AgentsBlood Component TransfusionBlood DonorsDNA, ViralGraft vs Host DiseaseHematologic NeoplasmsHematopoietic Stem Cell TransplantationHerpesvirus 4, HumanHumansImmunosuppression TherapyLymphocytesLymphoproliferative DisordersMalePolymerase Chain ReactionRituximabConceptsEpstein-Barr virus-associated lymphoproliferative disorderStem cell transplantationEBV DNA titersB cell populationsCell transplantationTherapeutic strategiesEpstein-Barr virus-associated lymphoproliferationHaplo-identical stem cell transplantationEffective alternative therapeutic strategyAllogeneic stem cell transplantationCourses of rituximabDonor-derived lymphocytesPost-transplant immunosuppressionMonoclonal B-cell populationCD20 monoclonal antibodyCell populationsAlternative therapeutic strategiesImmunosuppressive medicationsSevere GVHDHost diseaseLymphocyte infusionPost transplantFatal complicationCurative therapyLymphoproliferative disorders