2021
The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico.
Vermund SH, Febo I. The Historic Elimination of Mother-to-Child HIV and Syphilis Transmission in Puerto Rico. Puerto Rico Health Sciences Journal 2021, 40: 3-5. PMID: 33876911, PMCID: PMC8363137.Peer-Reviewed Original ResearchConceptsHigh background prevalenceElimination of HIVWorld Health OrganizationChildren HIVInfection overallPerinatal transmissionAntenatal servicesBackground prevalenceHIV riskSyphilis transmissionSyphilis therapyHIVHealth OrganizationSyphilisMothersPuerto RicoInfantsTherapyPrevalenceCareEliminationWomen
2018
Attrition of HIV‐exposed infants from early infant diagnosis services in low‐ and middle‐income countries: a systematic review and meta‐analysis
Carlucci JG, Liu Y, Friedman H, Pelayo BE, Robelin K, Sheldon EK, Clouse K, Vermund SH. Attrition of HIV‐exposed infants from early infant diagnosis services in low‐ and middle‐income countries: a systematic review and meta‐analysis. Journal Of The International AIDS Society 2018, 21: e25209. PMID: 30649834, PMCID: PMC6287094, DOI: 10.1002/jia2.25209.Peer-Reviewed Original ResearchConceptsEarly infant diagnosis servicesEID servicesMiddle-income countriesSystematic reviewRetention of HIVOptimal health outcomesNon-intervention studyMeta-regression analysisComprehensive database searchLTFU definitionStudy eligibilityMagnitude of attritionEligibility criteriaHIVDiagnosis serviceHealth outcomesInfantsRandom-effects meta-analytic methodsOverall attritionMeta-analytic methodsTime pointsData extractionVulnerable populationsImplementation researchMonths
2014
Correlates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria
Aliyu MH, Blevins M, Megazzini KM, Audet CM, Dunlap J, Sodangi IS, Gebi UI, Shepherd BE, Wester CW, Vermund SH. Correlates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: e19-e26. PMID: 24853310, PMCID: PMC4134378, DOI: 10.1097/qai.0000000000000215.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisRural North-Central NigeriaInfant diagnosisPregnant womenChild HIV transmission (PMTCT) programsHIV care/treatmentClinic of enrolmentPediatric HIV infectionPrevention of motherNorth Central NigeriaMultivariable logistic regressionCare/treatmentDate of enrollmentHIV service uptakeEID uptakeCohort studyHIV infectionLaboratory variablesClinic locationService uptakeMaternal factorsTransmission programInfantsReferral sourceLogistic regression
2012
Addressing Poor Retention of Infants Exposed to HIV
Ciampa PJ, Tique JA, Jumá N, Sidat M, Moon TD, Rothman RL, Vermund SH. Addressing Poor Retention of Infants Exposed to HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2012, 60: e46-e52. PMID: 22622077, PMCID: PMC3587032, DOI: 10.1097/qai.0b013e31824c0267.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisMother/infant pairsInfant pairsEnhanced referralProportion of HIVDays of lifePhase 2 groupProcess of referralLow-resource countriesPhase 2Phase 1Quality improvement effortsHIV carePostpartum dischargeInfant diagnosisAdjusted analysisCox regressionKaplan-MeierDistrict hospitalMedical recordsMAIN OUTCOMEQuality improvement methodsHIVInfantsReferral
2011
Improving Retention in the Early Infant Diagnosis of HIV Program in Rural Mozambique by Better Service Integration
Ciampa PJ, Burlison JR, Blevins M, Sidat M, Moon TD, Rothman RL, Vermund SH. Improving Retention in the Early Infant Diagnosis of HIV Program in Rural Mozambique by Better Service Integration. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 58: 115-119. PMID: 21546845, DOI: 10.1097/qai.0b013e31822149bf.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisInfant diagnosisInfant testingEarly infant testingWomen/infantsRetrospective record reviewPostpartum HIVRural MozambiqueRecord reviewStandard referralHIV programsHigher oddsReferral processSimple interventionHIVReferralDiagnosisInfant retentionWomenService integrationInfants
2009
Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol
Mwinga K, Vermund SH, Chen YQ, Mwatha A, Read JS, Urassa W, Carpenetti N, Valentine M, Goldenberg RL. Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol. BMC Pediatrics 2009, 9: 49. PMID: 19664210, PMCID: PMC2746190, DOI: 10.1186/1471-2431-9-49.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsBlood Cell CountDouble-Blind MethodFemaleFollow-Up StudiesGestational AgeHematocritHemoglobinsHIVHIV InfectionsHumansIncidenceInfantInfant, NewbornMalawiNevirapinePregnancyPregnancy Complications, InfectiousRetrospective StudiesRNA, ViralTanzaniaTreatment OutcomeYoung AdultZambiaConceptsHIV infectionPregnant African womenRandomized clinical trialsTime of laborComplete laboratory dataWeeks of ageNevirapine prophylaxisChild transmissionHIV exposureWeeks' gestationHIV statusPregnant womenNewborn infantsClinical trialsPublic clinicsHIVInfantsBiochemical measurementsCaucasian populationWomenLaboratory dataNormative dataAfrican womenInfectionWeeksPreventing HIV in Developing Countries: Status of Biomedical Interventions
Vermund S. Preventing HIV in Developing Countries: Status of Biomedical Interventions. The FASEB Journal 2009, 23: 199.1-199.1. DOI: 10.1096/fasebj.23.1_supplement.199.1.Peer-Reviewed Original ResearchHIV Prevention Trials NetworkPrevention of motherHIV drug resistanceNeedle exchange programsDNA boostBehavior changeHIV seroconversionHIV seroincidenceEarly therapyPregnant womenHSV-2Clinical trialsHIVMale circumcisionDrug addiction treatmentDrug resistanceTrials NetworkAddiction treatmentBiomedical interventionsSeroincidenceInfantsRisk reductionTherapyPrevention challengesEfficacy
2007
Early Infant Human Immunodeficiency Virus Type 1 Detection Suitable for Resource-Limited Settings with Multiple Circulating Subtypes by Use of Nested Three-Monoplex DNA PCR and Dried Blood Spots
Zhang Q, Wang L, Jiang Y, Fang L, Pan P, Gong S, Yao J, Tang YW, Vermund SH, Jia Y. Early Infant Human Immunodeficiency Virus Type 1 Detection Suitable for Resource-Limited Settings with Multiple Circulating Subtypes by Use of Nested Three-Monoplex DNA PCR and Dried Blood Spots. Journal Of Clinical Microbiology 2007, 46: 721-726. PMID: 18077639, PMCID: PMC2238144, DOI: 10.1128/jcm.01539-07.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBloodBlotting, WesternChinaDNA PrimersDNA, ViralEnv Gene Products, Human Immunodeficiency VirusGag Gene Products, Human Immunodeficiency VirusHIV AntibodiesHIV InfectionsHIV-1HumansInfantInfant, NewbornPol Gene Products, Human Immunodeficiency VirusPolymerase Chain ReactionReproducibility of ResultsSensitivity and SpecificitySpecimen HandlingConceptsHIV-1 subtypesMonths of ageDiverse HIV-1 subtypesEarly infant HIV-1 diagnosisHuman immunodeficiency virus type 1 (HIV-1) infectionHIV-1 DNA PCRVirus type 1 infectionDNA PCRType 1 infectionHIV-1 diagnosisDiverse HIV-1Resource limited settingsAntibody enzyme immunoassayBlood spot samplesInfected mothersMaternal antibodiesCRF01-AEDBS specimensEpidemiologic dataHIV-1Deceased infantsInfantsCRF07-BCMultiple subtypesBlood spots
2005
Mode of Delivery and Other Maternal Factors Influence the Acquisition of Streptococcus mutans in Infants
Li Y, Caufield PW, Dasanayake AP, Wiener HW, Vermund SH. Mode of Delivery and Other Maternal Factors Influence the Acquisition of Streptococcus mutans in Infants. Journal Of Dental Research 2005, 84: 806-811. PMID: 16109988, DOI: 10.1177/154405910508400905.Peer-Reviewed Original ResearchConceptsMode of deliveryMaternal factorsS. mutansC-section infantsMaternal gestational ageProspective cohort studyS. mutans levelsMother-infant pairsCaesarean sectionCohort studyPerinatal eventsGestational ageMutans levelsCariogenic microbiotaDental cariesPerinatal influencesInfection experienceInfantsCariesFamily incomeStreptococcus mutansMutansPotential effectsDeliveryInitial acquisition
2003
Prevention of mother-to-child transmission of HIV in Africa: successes and challenges in scaling-up a nevirapine-based program in Lusaka, Zambia
Stringer EM, Sinkala M, Stringer J, Mzyece E, Makuka I, Goldenberg RL, Kwape P, Chilufya M, Vermund SH. Prevention of mother-to-child transmission of HIV in Africa: successes and challenges in scaling-up a nevirapine-based program in Lusaka, Zambia. AIDS 2003, 17: 1377-1382. PMID: 12799559, PMCID: PMC2745990, DOI: 10.1097/00002030-200306130-00012.Peer-Reviewed Original ResearchConceptsPrevention of motherResource-limited settingsHIV infectionVoluntary counselingChild HIV transmissionPerinatal HIV infectionHIV prevention programsNVP therapyChild transmissionPatient attritionHIV transmissionPregnant womenPrevention programsNevirapineHIVHealth employeesThousands of womenTransmission routesLusakaMothersInfectionPreventionWomenCounselingInfants
2002
Perinatal HIV transmission: developing country considerations
Goldenberg RL, Stringer JS, Sinkala M, Vermund SH. Perinatal HIV transmission: developing country considerations. The Journal Of Maternal-Fetal & Neonatal Medicine 2002, 12: 149-158. PMID: 12530611, DOI: 10.1080/jmf.12.3.149.158.Peer-Reviewed Original ResearchConceptsMaternal HIV infectionMaternal-child transmissionObstetric care systemTransmission of HIVMortality rate 10HIV infectionAntiviral therapyPregnant womenChildhood mortalityInfantsHIVCare systemDevastating problemEarly childhoodInfectionMothersSubstantial additional resourcesTherapyMortalityPrevalenceWomen