2022
Revealing the human mucinome
Malaker SA, Riley NM, Shon DJ, Pedram K, Krishnan V, Dorigo O, Bertozzi CR. Revealing the human mucinome. Nature Communications 2022, 13: 3542. PMID: 35725833, PMCID: PMC9209528, DOI: 10.1038/s41467-022-31062-4.Peer-Reviewed Original ResearchConceptsModular protein domainsKey molecular signaturesProtein domainsTransmembrane proteinDetection of hundredsMucin domainGlycoprotein identificationHuman diseasesMolecular signaturesCell lysatesEnrichment strategyGlycoproteinVivo sourceOverlapping populationsImportant roleDomainStcEProteinLysatesOvarian cancer patientsComplex samples
2021
Novel “mucinomics” platform reveals molecular signatures of cancer in cellular systems and ovarian cancer patient ascites fluid
Malaker S, Riley N, Shon J, Pedram K, Bertozzi C. Novel “mucinomics” platform reveals molecular signatures of cancer in cellular systems and ovarian cancer patient ascites fluid. The FASEB Journal 2021, 35 DOI: 10.1096/fasebj.2021.35.s1.00426.Peer-Reviewed Original Research