2024
Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study
Powierza C, Doyle M, Wasden K, Intihar T, Korwin A, Honiden S, Knauert M. Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study. BMJ Open Respiratory Research 2024, 11: e001962. PMID: 38749534, PMCID: PMC11097881, DOI: 10.1136/bmjresp-2023-001962.Peer-Reviewed Original ResearchConceptsEarly enteral nutritionIn-hospital deathCritically ill adultsRetrospective cohort studyDays of intubationEnteral nutritionIll adultsAdult patientsCohort studyAssociated with decreased in-hospital deathsMechanically ventilated critically ill adultsGoal enteral nutritionIncreased hospital dischargeInitiation of ENCritically ill adult patientsMechanically ventilated adult patientsIncidence of in-hospital deathMedical intensive care unitAssociated with significant improvementsIll adult patientsDose of ENIntensive care unitClinical outcomesImprove mortalityPrimary outcome
2019
Reconsidering Nutritional Support in Critically Ill Patients
Korwin A, Honiden S. Reconsidering Nutritional Support in Critically Ill Patients. Seminars In Respiratory And Critical Care Medicine 2019, 40: 580-593. PMID: 31826259, DOI: 10.1055/s-0039-1697967.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCircadian RhythmCritical CareCritical IllnessEnteral NutritionHumansIntensive Care UnitsNutritional StatusNutritional SupportConceptsIntensive care unitIll patientsGood nutrition practicesNeeds of patientsProvision of nutritionICU nutritionSupportive careActive therapyNutritional supportCare unitFeeding interruptionsCritical careNutrition practicesGastrointestinal physiologyPatientsCircadian rhythmFeeding pumpProcess of recoveryCareMore researchNutritionProtein synthesisNon-continuous modeTherapyClinicians
2009
ICU Management of Acute Liver Failure
Schilsky ML, Honiden S, Arnott L, Emre S. ICU Management of Acute Liver Failure. Clinics In Chest Medicine 2009, 30: 71-87. PMID: 19186281, DOI: 10.1016/j.ccm.2008.10.001.Peer-Reviewed Original ResearchConceptsAcute liver failureLiver failureTeam approachGood ICU careOrganized team approachAcute liver injurySurvival of patientsBetter patient outcomesEarly disease recognitionLiver transplantationICU careLiver injuryICU managementPatient outcomesCritical carePatient managementSupportive measuresPatientsCareDisease recognitionICUTransplantationFailurePathophysiologyInjury
2008
Early versus late intravenous insulin administration in critically ill patients
Honiden S, Schultz A, Im SA, Nierman DM, Gong MN. Early versus late intravenous insulin administration in critically ill patients. Intensive Care Medicine 2008, 34: 881. PMID: 18180902, PMCID: PMC2486366, DOI: 10.1007/s00134-007-0978-3.Peer-Reviewed Original ResearchConceptsIntensive insulin therapyHospital mortalityICU admissionEarly therapyEarly intensive insulin therapyMore ventilator-free daysDecreased hospital mortalityLower ICU mortalityShorter ICU stayVentilator-free daysLower hospital mortalityProspective cohort studyShorter hospital stayTertiary teaching hospitalIntravenous insulin administrationPatientsThe studyAdmission diagnosisHospital stayICU mortalityICU stayCohort studyInsulin therapyMedical ICUDirection of associationIll patients
2007
Utilization of bronchodilators in ventilated patients without obstructive airways disease.
Chang LH, Honiden S, Haithcock JA, Das AM, Short KA, Nierman DM, Carson SS. Utilization of bronchodilators in ventilated patients without obstructive airways disease. Respiratory Care 2007, 52: 154-8. PMID: 17261202.Peer-Reviewed Original ResearchConceptsObstructive lung diseaseIntensive care unitLung diseaseCare unitMechanical ventilationStudy intensive care unitMedical intensive care unitTertiary care academic medical centerDays of intubationProspective cohort studyObstructive airways diseaseVentilator-associated pneumoniaIncidence of tachyarrhythmiasMean extra costAcademic medical centerAirway diseaseCohort studyIpratropium bromideBronchodilatorsMedical CenterPatientsDiseasePhysician practicesSubstantial proportionPneumonia