2023
Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning
Tran M, Tüshaus J, Kim Y, Ramazanov B, Devireddy S, Lichtenthaler S, Ferguson S, von Blume J. Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning. Traffic 2023, 24: 4-19. PMID: 36398980, PMCID: PMC9825660, DOI: 10.1111/tra.12873.Peer-Reviewed Original Research
2022
JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton
Rafiq N, Lyons L, Gowrishankar S, De Camilli P, Ferguson S. JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton. Communications Biology 2022, 5: 5. PMID: 35013510, PMCID: PMC8748971, DOI: 10.1038/s42003-021-02945-x.Peer-Reviewed Original Research
2000
Molecular Cloning of a Human, Hemicholinium-3-Sensitive Choline Transporter
Apparsundaram S, Ferguson S, George A, Blakely R. Molecular Cloning of a Human, Hemicholinium-3-Sensitive Choline Transporter. Biochemical And Biophysical Research Communications 2000, 276: 862-867. PMID: 11027560, DOI: 10.1006/bbrc.2000.3561.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBinding SitesBiological TransportCarrier ProteinsCholineChromosomes, Human, Pair 2Cloning, MolecularCOS CellsHemicholinium 3HumansLigandsMembrane Transport ProteinsMolecular Sequence DataOocytesProtein BindingRadiation Hybrid MappingRNA, MessengerSequence Homology, Amino AcidTransfectionXenopus laevisConceptsRadiation hybrid mapping techniquesCOS-7 cells resultsTransporter gene familyGlucose transporter gene familyHuman Genome ProjectNorthern blot analysisChromosomal localizationGene familyMolecular cloningGenome ProjectKb transcriptSequence informationMembrane vesiclesPrimary structureDependent choline uptakeMembrane fractionAmino acidsCDNAIodide transporterCells resultsBlot analysisChromosome 2q12Biosynthesis of acetylcholineMechanistic analysisCHO-1