2023
Histopathologic features and immunohistochemistry findings to assist the dermatopathologist in differentiating melanocytic matrical carcinoma from melanoma
Belzer A, Becerra C, Clune J, Malik M, Leventhal J, Cowper S, Johnson R. Histopathologic features and immunohistochemistry findings to assist the dermatopathologist in differentiating melanocytic matrical carcinoma from melanoma. Journal Of Cutaneous Pathology 2023, 50: 471-474. PMID: 36645720, DOI: 10.1111/cup.14376.Peer-Reviewed Original Research
2018
Detection of Borrelia in Ixodes scapularis ticks by silver stain, immunohistochemical and direct immunofluorescent methods
Galan A, Kupernik P, Cowper SE. Detection of Borrelia in Ixodes scapularis ticks by silver stain, immunohistochemical and direct immunofluorescent methods. Journal Of Cutaneous Pathology 2018, 45: 473-477. PMID: 29569269, DOI: 10.1111/cup.13143.Peer-Reviewed Original ResearchConceptsDirect immunofluorescent methodLyme diseaseImmunofluorescent methodSilver stainScapularis ticksPercentage of positivityRate of infectionCommon tick-borne diseasesIdentification of spirochetesDetection of BorreliaIxodes scapularis ticksClinical presentationRoutine biopsyClinical managementSkin biopsiesI. scapularis ticksConnecticut Agricultural Experiment StationTick-borne diseasesTick attachmentTimely identificationBiopsyDiseaseBorreliaSpirochetesStain
2017
Well‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63
Panse G, Cowper SE, Leffell DJ, Pulitzer M, Ko CJ. Well‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63. Journal Of Cutaneous Pathology 2017, 44: 557-562. PMID: 28417484, DOI: 10.1111/cup.12952.Peer-Reviewed Original ResearchConceptsCutaneous adnexal neoplasmsAdnexal neoplasmsNeuroendocrine tumorsAdnexal tumorsBenign skin adnexal tumorCutaneous adnexal tumorsAggressive metastatic diseaseLow-grade tumorsSkin adnexal tumorsMajority of casesMetastatic diseaseMetastatic adenocarcinomaCarcinoid tumorsCytokeratin 5/6Diagnostic challengeDifferential diagnosisImmunohistochemical stainsCK5/6Diagnostic utilityPrimary siteTumorsNeoplasmsFirst signWDNETsP63
2011
Mycosis fungoides exhibiting features of a dermatofibroma: a case report and review of the literature
Morcos SM, Girardi M, Subtil A, Wilson LD, Cowper SE. Mycosis fungoides exhibiting features of a dermatofibroma: a case report and review of the literature. Journal Of Cutaneous Pathology 2011, 39: 40-46. PMID: 22059953, DOI: 10.1111/j.1600-0560.2011.01804.x.Peer-Reviewed Case Reports and Technical NotesConceptsMycosis fungoidesLesions of MFStage IA mycosis fungoidesUnusual clinical presentationLarge cell transformationClinical cluesClinical presentationDermal lymphocytesPatient populationFibrohistiocytic proliferationCase reportClinical managementAtypical lesionsRight forearmSuspicious tumorsBenign lesionsLesionsFungoidesDermatofibromaPatientsPrognosisLymphocytesTumorsIntraepidermalPlaques
2007
Gadolinium is quantifiable within the tissue of patients with nephrogenic systemic fibrosis
High WA, Ayers RA, Cowper SE. Gadolinium is quantifiable within the tissue of patients with nephrogenic systemic fibrosis. Journal Of The American Academy Of Dermatology 2007, 56: 710-712. PMID: 17289213, DOI: 10.1016/j.jaad.2007.01.022.Peer-Reviewed Original Research
2005
CD56 staining in Merkel cell carcinoma and natural killer‐cell lymphoma: magic bullet, diagnostic pitfall, or both?
McNiff JM, Cowper SE, Lazova R, Subtil A, Glusac EJ. CD56 staining in Merkel cell carcinoma and natural killer‐cell lymphoma: magic bullet, diagnostic pitfall, or both? Journal Of Cutaneous Pathology 2005, 32: 541-545. PMID: 16115052, DOI: 10.1111/j.0303-6987.2005.00378.x.Peer-Reviewed Original ResearchConceptsNatural killer cell lymphomaNK-cell lymphomasMerkel cell carcinomaCases of MCCCD56 positivityCell carcinomaDiagnostic pitfallsDiagnosis of lymphomaCD20 negativityDense inflammationInflamed biopsiesNK lymphomaHistologic featuresMagic bulletNeuroendocrine tumorsCell lymphomaCD56Crush artifactSensitive markerLymphomaAdditional casesCarcinomaPositivityCK20MNF116Cellular digital fibromas: distinctive CD34‐positive lesions that may mimic dermatofibrosarcoma protuberans
McNiff JM, Subtil A, Cowper SE, Lazova R, Glusac EJ. Cellular digital fibromas: distinctive CD34‐positive lesions that may mimic dermatofibrosarcoma protuberans. Journal Of Cutaneous Pathology 2005, 32: 413-418. PMID: 15953374, DOI: 10.1111/j.0303-6987.2005.00358.x.Peer-Reviewed Original Research
2003
Nephrogenic fibrosing dermopathy: the first 6 years
Cowper SE. Nephrogenic fibrosing dermopathy: the first 6 years. Current Opinion In Rheumatology 2003, 15: 785-790. PMID: 14569211, DOI: 10.1097/00002281-200311000-00017.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNephrogenic fibrosing dermopathyRecent case reportsCase reportCutaneous fibrosing disorderYellow scleral plaquesDistinct clinical patternsDual immunohistochemical stainingAntiphospholipid antibodiesRenal insufficiencyClinical patternDual immunolabelingFibrosing disorderSystemic disordersClinical spectrumScleral plaquesDisease onsetEpidemiologic dataSpindle cellsImmunohistochemical stainingDisease triggersSkin conditionsDisease pathogenesisNormal skinRegistry projectDiagnostic tests
2002
Generalized bullae in an infant.
Chamlin SL, Cowper SE, Longley BJ, Williams ML. Generalized bullae in an infant. JAMA Dermatology 2002, 138: 831-6. PMID: 12056971.Peer-Reviewed Case Reports and Technical Notes
1999
p53, mdm-2, and p21 waf-1 in the Porokeratoses
Nelson C, Cowper S, Morgan M. p53, mdm-2, and p21 waf-1 in the Porokeratoses. American Journal Of Dermatopathology 1999, 21: 420. PMID: 10535569, DOI: 10.1097/00000372-199910000-00003.Peer-Reviewed Original ResearchConceptsTypes of porokeratosisCyclin-dependent kinase inhibitor p21P53 stainingP53 tumor suppressor gene productCornoid lamellaP21 expressionPorokeratosesCell cycle progressionMdm-2Waf-1Inhibitor p21Potential roleTumor suppressor gene productP53 tumor suppressor proteinP21 proteinSuppressor gene productCycle progressionMDM2Tumor suppressor proteinGene productsP53Cell cycle controlPrevious findingsP21Suppressor proteinExpression of p-27 (kip1) in Nevi and Melanomas
Morgan M, Cowper S. Expression of p-27 (kip1) in Nevi and Melanomas. American Journal Of Dermatopathology 1999, 21: 121-124. PMID: 10218670, DOI: 10.1097/00000372-199904000-00002.Peer-Reviewed Original ResearchConceptsExpression of p27Melanocytic lesionsSpitz neviDistribution of immunoreactivityP27 labeling indexMinority of casesCell cycle inhibitory proteinsChart reviewMalignant melanocytic lesionsClinical historyDiagnostic challengeBiologic behaviorHistopathologic criteriaLabeling indexCompound neviLogistic regressionHuman neoplasmsNeviNuclear stainingLesionsMelanomaP27Inhibitory proteinAccurate distinctionSkin