2014
Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African Trypanosomiasis
Initiative I, Attardo G, Abila P, Auma J, Baumann A, Benoit J, Brelsfoard C, Ribeiro J, Cotton J, Pham D, Darby A, Van Den Abbeele J, Denlinger D, Field L, Nyanjom S, Gaunt M, Geiser D, Gomulski L, Haines L, Hansen I, Jones J, Kibet C, Kinyua J, Larkin D, Lehane M, Rio R, Macdonald S, Macharia R, Malacrida A, Marco H, Marucha K, Masiga D, Meuti M, Mireji P, Obiero G, Koekemoer J, Okoro C, Omedo I, Osamor V, Balyeidhusa A, Peyton J, Price D, Quail M, Ramphul U, Rawlings N, Riehle M, Robertson H, Sanders M, Scott M, Dashti Z, Snyder A, Srivastava T, Stanley E, Swain M, Hughes D, Tarone A, Taylor T, Telleria E, Thomas G, Walshe D, Wilson R, Winzerling J, Acosta-Serrano A, Aksoy S, Arensburger P, Aslett M, Bateta R, Benkahla A, Berriman M, Bourtzis K, Caers J, Caljon G, Christoffels A, Falchetto M, Friedrich M, Fu S, Gäde G, Githinji G, Gregory R, Hall N, Harkins G, Hattori M, Hertz-Fowler C, Hide W, Hu W, Imanishi T, Inoue N, Jonas M, Kawahara Y, Koffi M, Kruger A, Lawson D, Lehane S, Lehväslaiho H, Luiz T, Makgamathe M, Malele I, Manangwa O, Manga L, Megy K, Michalkova V, Mpondo F, Mramba F, Msangi A, Mulder N, Murilla G, Mwangi S, Okedi L, Ommeh S, Ooi C, Ouma J, Panji S, Ravel S, Rose C, Sakate R, Schoofs L, Scolari F, Sharma V, Sim C, Siwo G, Solano P, Stephens D, Suzuki Y, Sze S, Touré Y, Toyoda A, Tsiamis G, Tu Z, Wamalwa M, Wamwiri F, Wang J, Warren W, Watanabe J, Weiss B, Willis J, Wincker P, Zhang Q, Zhou J. Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African Trypanosomiasis. Science 2014, 344: 380-386. PMID: 24763584, PMCID: PMC4077534, DOI: 10.1126/science.1249656.Peer-Reviewed Original ResearchConceptsGenome sequenceLactation-specific proteinsProtein-encoding genesBacterial genome sequencesPathogen recognition proteinsTsetse fliesMicrobial symbiosesTsetse biologyViviparous reproductionGenome dataRecognition proteinsSole vectorsChromosomal integrationDisease vectorsAfrican trypanosomiasisGenomeGenesFliesProteinSequenceMultiple aspectsHuman African trypanosomiasisImportant insightsMultiple discoveriesSymbioses
2002
Tsetse Vector Based Strategies for Control of African Try Panosomiasis
Aksoy S. Tsetse Vector Based Strategies for Control of African Try Panosomiasis. 2002, 1: 39-49. DOI: 10.1007/0-306-46894-8_4.Peer-Reviewed Original ResearchMolecular genetic approachesBacterial symbiontsRecombinant DNA technologySymbiotic bacteriaCytoplasmic incompatibilityWolbachia symbiontsPotential genesGenetic approachesParasite biologyForeign genesSusceptible counterpartsDNA technologySymbiontsGenesSame tissueInsectsDisease transmissionOrganismsBiologyTrypanosomesBacteriaExpressionNew strategyTsetse
2001
Tsetse immune responses and trypanosome transmission: Implications for the development of tsetse-based strategies to reduce trypanosomiasis
Hao Z, Kasumba I, Lehane M, Gibson W, Kwon J, Aksoy S. Tsetse immune responses and trypanosome transmission: Implications for the development of tsetse-based strategies to reduce trypanosomiasis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 12648-12653. PMID: 11592981, PMCID: PMC60108, DOI: 10.1073/pnas.221363798.Peer-Reviewed Original ResearchConceptsFat bodyInsect immune systemAntimicrobial peptide genesFat body tissueImmune responsive genesDifferent life stagesTransgenic approachesResponsive genesAntimicrobial genesImmune responseSubtractive cloningPeptide genesAfrican trypanosomesMolecular signalsImmune systemDifferential regulationInfection processLife stagesTrypanosome transmissionParasite transmissionGenesImportant vectorEscherichia coliBiochemical natureDiptericin
1997
Genetic manipulation of insect symbionts
Beard C, Aksoy S. Genetic manipulation of insect symbionts. 1997, 555-560. DOI: 10.1007/978-94-009-1535-0_45.Peer-Reviewed Original Research
1992
Spliced leader RNA sequences of Trypanosoma rangeli are organized within the 5S rRNA-encoding genes
Aksoy S, Shay G, Villaneuva M, Beard C, Richards F. Spliced leader RNA sequences of Trypanosoma rangeli are organized within the 5S rRNA-encoding genes. Gene 1992, 113: 239-243. PMID: 1572544, DOI: 10.1016/0378-1119(92)90401-a.Peer-Reviewed Original Research
1991
A New Member of a Family of Site-Specific Retrotransposons Is Present in the Spliced Leader RNA Genes of Trypanosoma cruzi
Villanueva M, Williams S, Beard C, Richards F, Aksoy S. A New Member of a Family of Site-Specific Retrotransposons Is Present in the Spliced Leader RNA Genes of Trypanosoma cruzi. Molecular And Cellular Biology 1991, 11: 6139-6148. DOI: 10.1128/mcb.11.12.6139-6148.1991.Peer-Reviewed Original Research