Extracapsular extension is not a significant prognostic indicator in non-squamous cancers of the major salivary glands
Cheraghlou S, Yu PK, Otremba MD, Mehra S, Yarbrough WG, Judson BL. Extracapsular extension is not a significant prognostic indicator in non-squamous cancers of the major salivary glands. Cancers Of The Head & Neck 2018, 3: 5. PMID: 31093358, PMCID: PMC6460801, DOI: 10.1186/s41199-018-0032-x.Peer-Reviewed Original ResearchSignificant prognostic indicatorPrognostic indicatorMajor salivary glandsAdverse featuresSalivary cancerPrognostic valueECE statusUnivariate Kaplan-Meier analysisAdditional adverse featuresCox survival regressionNode-positive cancersNon-squamous cancersPost-operative radiotherapyHigh-risk featuresSalivary glandsPositive surgical marginsKaplan-Meier analysisSquamous cell cancerSalivary gland cancerSCC patientsMucosal headWorse survivalImproved survivalSurgical marginsCell cancerPediatric Salivary Cancer: Epidemiology, Treatment Trends, and Association of Treatment Modality with Survival
Morse E, Fujiwara RJT, Husain Z, Judson B, Mehra S. Pediatric Salivary Cancer: Epidemiology, Treatment Trends, and Association of Treatment Modality with Survival. Otolaryngology 2018, 159: 553-563. PMID: 29688836, DOI: 10.1177/0194599818771926.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBiopsy, NeedleCarcinoma, MucoepidermoidChemotherapy, AdjuvantChildChild, PreschoolCombined Modality TherapyCross-Sectional StudiesDatabases, FactualFemaleHumansImmunohistochemistryLogistic ModelsMaleMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingPrognosisProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesSalivary Gland NeoplasmsSurvival AnalysisTreatment OutcomeConceptsImproved overall survivalOverall survivalHigh tumor gradeTreatment modalitiesTumor gradeSalivary cancerAdjuvant radiationMultivariable Cox proportional hazards regressionNational Cancer Database 2004Cox proportional hazards regressionTreatment factorsPatients 19 yearsHigh-risk patientsSubset of patientsMultivariable logistic regressionProportional hazards regressionUS national databaseHigh-grade tumorsSalivary gland cancerAcinar cell carcinomaPediatric patientsTumor characteristicsHazards regressionCell carcinomaGland cancerTreatment Times in Salivary Gland Cancer: National Patterns and Association with Survival
Morse E, Fujiwara RJT, Judson B, Mehra S. Treatment Times in Salivary Gland Cancer: National Patterns and Association with Survival. Otolaryngology 2018, 159: 283-292. PMID: 29460669, DOI: 10.1177/0194599818758020.Peer-Reviewed Original ResearchConceptsOverall survivalSalivary cancerTotal treatment packageMedian durationRT durationTreatment initiationRadiation treatmentTreatment characteristicsMultivariable Cox proportional hazards regressionCox proportional hazards regressionMultivariable binary logistic regressionNational Cancer DatabaseProportional hazards regressionSalivary gland cancerTreatment packageBinary logistic regressionTherapy durationInitial treatmentFacility volumeHazards regressionFourth quartileCare transitionsGland cancerInsurance statusCancer Database