Featured Publications
Positive margin rates and predictors in transoral robotic surgery after federal approval: A national quality study
Hanna J, Morse E, Brauer PR, Judson B, Mehra S. Positive margin rates and predictors in transoral robotic surgery after federal approval: A national quality study. Head & Neck 2019, 41: 3064-3072. PMID: 31058417, DOI: 10.1002/hed.25792.Peer-Reviewed Original ResearchConceptsPositive margin rateTransoral robotic surgeryLow positive margin rateLow-volume facilitiesHigh-volume facilitiesPositive marginsT classificationMargin rateHuman papilloma virus (HPV) statusRobotic surgeryLymph-vascular invasionNational Cancer DatabaseMargin statusRetrospective reviewTumor subsiteVirus statusCancer DatabaseMultivariable regressionLinear associationPatientsSurgeryQuality studiesStatusAssociation
2024
The Impact of Four Smoking Metrics on Survival After Diagnosis with HPV+ Oropharyngeal Cancer
Wilkins S, Shah R, Safranek C, Shah H, Mehra S. The Impact of Four Smoking Metrics on Survival After Diagnosis with HPV+ Oropharyngeal Cancer. The Laryngoscope 2024, 134: 3158-3164. PMID: 38294283, DOI: 10.1002/lary.31319.Peer-Reviewed Original ResearchOropharyngeal squamous cell carcinomaRecurrence-free survivalHPV+ oropharyngeal squamous cell carcinomaOverall survivalPack-yearsTobacco useRetrospective review of patientsImpact overall survivalReview of patientsSquamous cell carcinomaSmoking metricsInferior OSImpact of tobacco useMetastatic diseaseImpact of smokingPrognostic significanceRetrospective reviewCell carcinomaSmoking historyUnivariate analysisNever-smokersMultivariate analysisSmoking statusPatientsInclusion criteria
2019
Margins in Laryngeal Squamous Cell Carcinoma Treated with Transoral Laser Microsurgery: A National Database Study
Hanna J, Brauer PR, Morse E, Mehra S. Margins in Laryngeal Squamous Cell Carcinoma Treated with Transoral Laser Microsurgery: A National Database Study. Otolaryngology 2019, 161: 986-992. PMID: 31476984, DOI: 10.1177/0194599819874315.Peer-Reviewed Original ResearchConceptsPositive margin rateLaryngeal squamous cell carcinomaPercent of patientsSquamous cell carcinomaPositive marginsTransoral laser microsurgeryMargin rateMargin statusT stageCell carcinomaNational Cancer DatabaseNational database studyMultivariable logistic regressionProper patient selectionEquivalent survival benefitLaser microsurgeryLaryngeal laser surgeryMicrosurgery resectionT3 tumorsNonacademic centersSurvival benefitGlottic tumorsMultivariable analysisPatient selectionRetrospective reviewEpidemiological analysis of croup in the emergency department using two national datasets
Hanna J, Brauer PR, Morse E, Berson E, Mehra S. Epidemiological analysis of croup in the emergency department using two national datasets. International Journal Of Pediatric Otorhinolaryngology 2019, 126: 109641. PMID: 31442871, DOI: 10.1016/j.ijporl.2019.109641.Peer-Reviewed Original ResearchConceptsEmergency Department SampleEmergency departmentReadmission ratesNational Hospital Ambulatory Medical Care SurveyAmbulatory Medical Care SurveyNational Emergency Department SampleNationwide Emergency Department SampleCases of croupHospital admission ratesInappropriate antibiotic useIncidence of croupMajority of casesRepeat admissionsSteroid usageHospital admissionAirway proceduresAnnual incidenceRetrospective reviewMean agePeak incidenceCare SurveyAdmission ratesAntibiotic useAntibiotic usageAverage age
2017
Untreated oral cavity cancer: Long‐term survival and factors associated with treatment refusal
Cheraghlou S, Kuo P, Mehra S, Yarbrough WG, Judson BL. Untreated oral cavity cancer: Long‐term survival and factors associated with treatment refusal. The Laryngoscope 2017, 128: 664-669. PMID: 28865100, DOI: 10.1002/lary.26809.Peer-Reviewed Original ResearchConceptsOral cavity cancerNatural courseTreatment refusalUnivariate Kaplan-Meier analysisFive-year survival rateFacility case volumeNational Cancer DatabaseStage 4 patientsExtent of diseaseMultivariate Cox regressionEarly-stage patientsKaplan-Meier analysisNumber of patientsCommon malignant diseaseLong-term survivalInitial treatment planningAdvanced diseaseUntreated patientsAdult patientsRetrospective reviewCox regressionPatient's likelihoodPoor prognosisInsurance statusMalignant disease
2014
Extrathyroidal Extension Predicts Extranodal Extension in Patients with Positive Lymph Nodes: An Important Association That May Affect Clinical Management
Clain JB, Scherl S, Dos Reis L, Turk A, Wenig BM, Mehra S, Karle WE, Urken ML. Extrathyroidal Extension Predicts Extranodal Extension in Patients with Positive Lymph Nodes: An Important Association That May Affect Clinical Management. Thyroid 2014, 24: 951-957. PMID: 24443878, DOI: 10.1089/thy.2013.0557.Peer-Reviewed Original ResearchConceptsExtranodal extensionLymph nodesPrimary tumorPresence of ENEAmerican Pathologists (CAP) protocolNode-positive patientsPositive lymph nodesRecurrent lymph nodesUpstaging of patientsMajority of patientsAggressive disease biologyLong-term survivalPresence of extensionCompletion thyroidectomyPositive nodesNodal metastasisRetrospective reviewHistologic featuresClinical managementDisease aggressivenessThyroid cancerT4 casesThyroid carcinomaHigh incidencePatients