Featured Publications
Characteristics and Outcomes of Sepsis Presenting in Inpatient Pediatric Settings.
Schafer M, Gruhler De Souza H, Paul R, Riggs R, Richardson T, Conlon P, Duffy S, Foster L, Gunderson J, Hall D, Hatcher L, Hess L, Kirkpatrick L, Kunar J, Lockwood J, Lowerre T, McFadden V, Raghavan A, Rizzi J, Stephen R, Stokes S, Workman J, Kandil S. Characteristics and Outcomes of Sepsis Presenting in Inpatient Pediatric Settings. Hospital Pediatrics 2022, 12: 1048-1059. PMID: 36345706, DOI: 10.1542/hpeds.2022-006592.Peer-Reviewed Original ResearchConceptsSepsis-attributable mortalitySepsis casesVasopressor useInpatient casesRetrospective cohort studyIntensive care admissionInpatient pediatric settingLonger lengthSepsis literatureTreatment bundleCare admissionInpatient cohortBundle adherenceClinical characteristicsCohort studySepsis outcomeSepsis recognitionChildren's HospitalIntensive careMortality outcomesLeading causeInpatient settingPediatric settingData registryED cases
2023
Bundled Care to Reduce Sepsis Mortality: The Improving Pediatric Sepsis Outcomes (IPSO) Collaborative.
Paul R, Niedner M, Riggs R, Richardson T, DeSouza H, Auletta J, Balamuth F, Campbell D, Depinet H, Hueschen L, Huskins W, Kandil S, Larsen G, Mack E, Priebe G, Rutman L, Schafer M, Scott H, Silver P, Stalets E, Wathen B, Macias C, Brilli R. Bundled Care to Reduce Sepsis Mortality: The Improving Pediatric Sepsis Outcomes (IPSO) Collaborative. Pediatrics 2023, 152 PMID: 37435672, DOI: 10.1542/peds.2022-059938.Peer-Reviewed Original ResearchConceptsSepsis-attributable mortalityCare bundleSepsis outcomeSepsis patientsEvidence-based care bundleChildren's Hospital AssociationGreater mortality reductionHospital AssociationSepsis care bundlesIC cohortISS cohortSepsis mortalityOrgan dysfunctionSepsis bundleSeptic shockPediatric sepsisChildren's HospitalSpecial cause variationBundle complianceMortality reductionImproved outcomesTimely treatmentPearson χKruskal-Wallis testMortality