1841. Younger age and female gender are associated with delayed antibiotics in pediatric sepsis
Kandil S, Lee S, Feinn R, Murray T. 1841. Younger age and female gender are associated with delayed antibiotics in pediatric sepsis. Open Forum Infectious Diseases 2023, 10: ofad500.1669. PMCID: PMC10678741, DOI: 10.1093/ofid/ofad500.1669.Peer-Reviewed Original ResearchAntibiotic administrationSepsis severityFemale genderNeonatal intensive care unitRetrospective cohort reviewDiagnosis of sepsisIntensive care unitExposure of interestChi-square testingPediatric sepsis mortalityIntravenous antibioticsCare bundleICU admissionCohort reviewSepsis mortalitySepsis recognitionPrimary outcomeCare unitFemale patientsHospital diagnosisLevel carePediatric sepsisAntibiotic delayBackground SepsisPediatric mortalityBundled Care to Reduce Sepsis Mortality: The Improving Pediatric Sepsis Outcomes (IPSO) Collaborative.
Paul R, Niedner M, Riggs R, Richardson T, DeSouza H, Auletta J, Balamuth F, Campbell D, Depinet H, Hueschen L, Huskins W, Kandil S, Larsen G, Mack E, Priebe G, Rutman L, Schafer M, Scott H, Silver P, Stalets E, Wathen B, Macias C, Brilli R. Bundled Care to Reduce Sepsis Mortality: The Improving Pediatric Sepsis Outcomes (IPSO) Collaborative. Pediatrics 2023, 152 PMID: 37435672, DOI: 10.1542/peds.2022-059938.Peer-Reviewed Original ResearchConceptsSepsis-attributable mortalityCare bundleSepsis outcomeSepsis patientsEvidence-based care bundleChildren's Hospital AssociationGreater mortality reductionHospital AssociationSepsis care bundlesIC cohortISS cohortSepsis mortalityOrgan dysfunctionSepsis bundleSeptic shockPediatric sepsisChildren's HospitalSpecial cause variationBundle complianceMortality reductionImproved outcomesTimely treatmentPearson χKruskal-Wallis testMortality