2022
Symptom cluster profiles following traumatic orthopaedic injuries
Breazeale S, Conley S, Jeon S, Dorsey SG, Kearney J, Yoo B, Redeker NS. Symptom cluster profiles following traumatic orthopaedic injuries. Injury 2022, 53: 2524-2532. PMID: 35351294, PMCID: PMC9232974, DOI: 10.1016/j.injury.2022.03.030.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyBrain-Derived Neurotrophic FactorDepressionFemaleHumansMusculoskeletal SystemPainPsychological DistressSyndromeConceptsBrain-derived neurotrophic factorSerum BDNF concentrationsTraumatic orthopaedic injuriesAcute stress disorderBDNF concentrationsEnzyme-linked immunosorbent assayRs6265 genotypeClinical characteristicsOrthopedic injuriesSymptoms of ASDOutcomes Measurement Information System Short FormsSelf-identified black raceAcute Stress Disorder ScaleHours of injuryPost-injury symptomsSevere psychological distressSymptoms of anxietySymptom burdenSymptom screeningNeurotrophic factorBlack raceFemale sexSleep disturbancesReal-time PCRHigher odds
2020
Symptom cluster profiles following traumatic orthopedic injuries: A protocol
Breazeale S, Dorsey SG, Kearney J, Conley S, Jeon S, Yoo B, Redeker NS. Symptom cluster profiles following traumatic orthopedic injuries: A protocol. Research In Nursing & Health 2020, 44: 268-278. PMID: 33368378, PMCID: PMC7933085, DOI: 10.1002/nur.22102.Peer-Reviewed Original ResearchMeSH KeywordsBrain-Derived Neurotrophic FactorCross-Sectional StudiesFractures, BoneHumansResearch DesignSleep Wake DisordersSyndromeConceptsBrain-derived neurotrophic factorTraumatic orthopaedic injuriesStressor-related disordersSerum concentrationsSleep disturbancesOrthopedic injuriesLong-term outcomesCross-sectional studyVal66Met mutationLow serum concentrationsSymptoms of anxietyPotential biological mechanismsPostinjury symptomsClinical factorsNegative long-term outcomesNeurotrophic factorBDNF geneTraumatic injuryHigh riskMillions of AmericansHealthcare costsMore symptomsInjurySymptomsPain