Do craniopharyngioma molecular signatures correlate with clinical characteristics?
Omay SB, Chen YN, Almeida JP, Ruiz-Treviño AS, Boockvar JA, Stieg PE, Greenfield JP, Souweidane MM, Kacker A, Pisapia DJ, Anand VK, Schwartz TH. Do craniopharyngioma molecular signatures correlate with clinical characteristics? Journal Of Neurosurgery 2017, 128: 1473-1478. PMID: 28707994, DOI: 10.3171/2017.1.jns162232.Peer-Reviewed Original ResearchConceptsPapillary craniopharyngiomasAdamantinomatous craniopharyngiomaMutation groupPostoperative clinical symptomsSubgroup of tumorsMolecular signaturesWeill Cornell Medical CollegeND tumorsClinical characteristicsCornell Medical CollegeClinical symptomsClinical variablesGroup tumorsRadiographic featuresResults HistologyBRAF mutationsCraniopharyngiomaAge groupsMedical CollegeTumorsExome sequencing studiesCTNNB1 mutationsOutcome variablesHistologyPatientsEndonasal endoscopic pituitary surgery in the elderly.
Wilson PJ, Omay SB, Kacker A, Anand VK, Schwartz TH. Endonasal endoscopic pituitary surgery in the elderly. Journal Of Neurosurgery 2017, 128: 429-436. PMID: 28387628, DOI: 10.3171/2016.11.jns162286.Peer-Reviewed Original ResearchMeSH KeywordsAdenomaAgedAged, 80 and overBlood Loss, SurgicalDatabases, FactualFemaleHumansLength of StayMaleMiddle AgedNasal CavityNatural Orifice Endoscopic SurgeryNeurosurgical ProceduresPituitary GlandPituitary NeoplasmsPostoperative ComplicationsRetrospective StudiesSphenoid BoneTreatment OutcomeConceptsComplication rateEndonasal endoscopic surgeryElderly patientsPituitary adenomasEndoscopic surgeryEndoscopic endonasal transsphenoidal resectionAge groupsEndonasal transsphenoidal resectionSymptomatic subdural hygromasIntraoperative blood lossRisk of complicationsRisk of surgeryExtent of resectionSingle-center dataAverage tumor diameterHealthy young personsLength of stayEndonasal endoscopic pituitary surgeryEndonasal endoscopic approachEndoscopic pituitary surgeryCranial complicationsPostoperative hematomaSymptomatic patientsBlood lossRetrospective review