Sachira Denagamage
Research
Publications
2024
Widespread receptive field remapping in early primate visual cortex
Denagamage S, Morton M, Hudson N, Nandy A. Widespread receptive field remapping in early primate visual cortex. Cell Reports 2024, 43: 114557. PMID: 39058592, DOI: 10.1016/j.celrep.2024.114557.Peer-Reviewed Original ResearchEarly visual cortexVisual cortexReceptive fieldsArea V2Tuning properties of neuronsPrimate visual cortexCued saccade taskVisual area V2Tuning propertiesPredictive remappingProperties of neuronsEye movementsRemappingCortical layersCell typesNeuronsSaccadic eye movementsCortical areasPerceptual stabilityCortexCurrent modelsSaccade task
2023
Laminar mechanisms of saccadic suppression in primate visual cortex
Denagamage S, Morton M, Hudson N, Reynolds J, Jadi M, Nandy A. Laminar mechanisms of saccadic suppression in primate visual cortex. Cell Reports 2023, 42: 112720. PMID: 37392385, PMCID: PMC10528056, DOI: 10.1016/j.celrep.2023.112720.Peer-Reviewed Original ResearchConceptsSaccadic suppressionFiring rateInter-neuronal correlationsLocal inhibitory activityCortical firing ratesEye movementsSaccadic eye movementsPutative inhibitory interneuronsDistinct neural subpopulationsVisual cortical networkPrimate visual cortexVisual area V4Inhibitory interneuronsCortical circuitryVisual cortexSaccade onsetArea V4Single neuronsCortical networksNeural subpopulationsVisual stabilityNeuronsInhibitory activityTemporary reductionVisual sensitivity
2018
HOPE: Hybrid-Drive Combining Optogenetics, Pharmacology and Electrophysiology
Delcasso S, Denagamage S, Britton Z, Graybiel A. HOPE: Hybrid-Drive Combining Optogenetics, Pharmacology and Electrophysiology. Frontiers In Neural Circuits 2018, 12: 41. PMID: 29872379, PMCID: PMC5972628, DOI: 10.3389/fncir.2018.00041.Peer-Reviewed Original ResearchConceptsHuman cognitionNeural mechanismsBehavioral trainingBrain activitySystems neuroscienceBrain regionsNeuroscienceCutting-edge experimentsElectrophysiological recordingsPrecise representationBrain pathologyOptogenetic manipulationMouse brain regionsDifferent mouse brain regionsCognitionCausal factorsBrain surgeryInjection cannulaMouse modelSpecific needsResearch teamElectrophysiologyTrainingMicePharmacology
2016
Graphene-Templated Synthesis of Magnetic Metal Organic Framework Nanocomposites for Selective Enrichment of Biomolecules
Cheng G, Wang Z, Denagamage S, Zheng S. Graphene-Templated Synthesis of Magnetic Metal Organic Framework Nanocomposites for Selective Enrichment of Biomolecules. ACS Applied Materials & Interfaces 2016, 8: 10234-10242. PMID: 27046460, DOI: 10.1021/acsami.6b02209.Peer-Reviewed Original ResearchConceptsHigh specific surface areaLow-concentration biomoleculesMetal-organic framework nanocompositesSelective extractionUnique porous structureMagnetic metal–organic framework nanocompositesMetal–organic framework (MOF) layerOrganic framework nanocompositesHigh saturation magnetizationSpecific surface areaComposite materialsAverage pore sizeGraphene nanosheetsMagnetic nanoparticlesPrepared composite materialNovel magneticGrapheneAffinity materialsMOF compositesMultifunctional compositesPorous MOFsMetal ionsCarboxylic groupsUniversal affinityPorous structure