2019
ImmuneRegulation: a web-based tool for identifying human immune regulatory elements
Kalayci S, Selvan ME, Ramos I, Cotsapas C, Harris E, Kim EY, Montgomery RR, Poland G, Pulendran B, Tsang JS, Klein RJ, Gümüş ZH. ImmuneRegulation: a web-based tool for identifying human immune regulatory elements. Nucleic Acids Research 2019, 47: w142-w150. PMID: 31114925, PMCID: PMC6602512, DOI: 10.1093/nar/gkz450.Peer-Reviewed Original Research
2016
Age-related alterations in immune responses to West Nile virus infection
Montgomery R. Age-related alterations in immune responses to West Nile virus infection. Clinical & Experimental Immunology 2016, 187: 26-34. PMID: 27612657, PMCID: PMC5167051, DOI: 10.1111/cei.12863.Peer-Reviewed Original ResearchConceptsWest Nile virusToll-like receptorsDendritic cellsSevere diseaseBlood-brain barrier permeabilityImportant public health concernWest Nile virus infectionHuman dendritic cellsNatural killer cellsAnti-viral responseMonocytes/macrophagesPathogen recognition receptorsAge-related alterationsSpecific immune parametersPublic health concernImportant causative agentAge-related impairmentIndividual host factorsAge-related changesKiller cellsViral encephalitisImmune cellsRisk factorsBarrier permeabilityHigh prevalence
2015
Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility
Strauss-Albee DM, Fukuyama J, Liang EC, Yao Y, Jarrell JA, Drake AL, Kinuthia J, Montgomery RR, John-Stewart G, Holmes S, Blish CA. Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility. Science Translational Medicine 2015, 7: 297ra115. PMID: 26203083, PMCID: PMC4547537, DOI: 10.1126/scitranslmed.aac5722.Peer-Reviewed Original ResearchConceptsAntiviral responseInnate natural killer (NK) cellsNK cell repertoire diversityHIV-1 acquisitionNatural killer cellsOutcome of infectionNK cellsWest Nile virusAntitumor responseKiller cellsCytokine productionInhibitory receptorsImmune historyImmune experienceHIV-1Repertoire diversityViral susceptibilityNile virusAfrican womenExposure riskFunctional consequencesTerminal differentiationRiskSingle-cell levelCells
2008
RNA interference screen for human genes associated with West Nile virus infection
Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, Montgomery RR, Lev S, Mason PW, Koski RA, Elledge SJ, Xavier RJ, Agaisse H, Fikrig E. RNA interference screen for human genes associated with West Nile virus infection. Nature 2008, 455: 242-245. PMID: 18690214, PMCID: PMC3136529, DOI: 10.1038/nature07207.Peer-Reviewed Original ResearchMeSH KeywordsComputational BiologyDengue VirusEndoplasmic ReticulumGene Expression ProfilingGenome, HumanHeLa CellsHIVHumansImmunityMonocarboxylic Acid TransportersMuscle ProteinsProtein BindingRNA InterferenceUbiquitin-Protein LigasesUbiquitinationVesiculovirusVirus ReplicationWest Nile FeverWest Nile virus