2018
Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes
Wang X, Malawista A, Qian F, Ramsey C, Allore HG, Montgomery RR. Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes. Oncotarget 2018, 9: 9572-9580. PMID: 29515754, PMCID: PMC5839385, DOI: 10.18632/oncotarget.23851.Peer-Reviewed Original ResearchReceptor-mediated immune responsesChronic tissue inflammationAge-dependent differencesAge-related changesImmune deteriorationChronic inflammationTissue inflammationTAM receptorsImmune responseImmune stimulationInflammatory regulatorsTAM familyComplex dysregulationInflammationReceptor tyrosine kinasesOlder adultsElevated expressionCytokine receptorsMonocytesReceptorsTyrosine kinaseMediator AktNegative regulatorResponseExpression
2016
Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny
Malawista A, Wang X, Trentalange M, Allore HG, Montgomery RR. Coordinated expression of tyro3, axl, and mer receptors in macrophage ontogeny. Macrophage 2016, 3: e1261. PMID: 27695708, PMCID: PMC5040214, DOI: 10.14800/macrophage.1261.Peer-Reviewed Original ResearchTAM receptorsTherapeutic interventionsTAM receptor expressionPro-inflammatory cytokinesToll-like receptorsPotential therapeutic interventionsSignificant differencesMacrophage ontogenyUpregulation of expressionTriple-mutant miceLymphoproliferative disordersHomologous receptor tyrosine kinasesTAM expressionReceptor expressionM receptorMutant miceHuman macrophagesMonocytesReceptor tyrosine kinasesMacrophagesAxlProtein levelsReceptorsTyro3Human subjects
2014
Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling
Lee N, Shin MS, Kang KS, Yoo SA, Mohanty S, Montgomery RR, Shaw AC, Kang I. Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling. Clinical Immunology 2014, 152: 101-110. PMID: 24657713, PMCID: PMC4018768, DOI: 10.1016/j.clim.2014.03.003.Peer-Reviewed Original Research
2004
TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferi
Pal U, Li X, Wang T, Montgomery RR, Ramamoorthi N, deSilva AM, Bao F, Yang X, Pypaert M, Pradhan D, Kantor FS, Telford S, Anderson JF, Fikrig E. TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferi. Cell 2004, 119: 457-468. PMID: 15537536, DOI: 10.1016/j.cell.2004.10.027.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAntibodies, BacterialAntigens, SurfaceBacterial Outer Membrane ProteinsBacterial VaccinesBase SequenceBorrelia burgdorferiCloning, MolecularGene Expression RegulationHost-Parasite InteractionsIntestinesIxodesLipoproteinsMiceMice, Inbred C3HMolecular Sequence DataReceptors, Cell SurfaceRecombinant ProteinsConceptsLyme disease agent Borrelia burgdorferiSurvival of spirochetesTick receptorMammalian hostsRNA interferenceEfficient colonizationTROSPAOuter surface protein ABorrelia burgdorferiPathogen adherencePathogen transmissionProtein AB. burgdorferi outer surface protein AMRNA levelsIxodes scapularisB. burgdorferiColonizationSurface protein AReceptorsArthropodsBurgdorferiMammalsRepressionSpirochetesTicks