2023
Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study
Datta R, Han L, Doyle M, Allore H, Sanft T, Quagliarello V, Juthani-Mehta M. Antibiotic therapy is associated with adverse drug events among older adults with advanced cancer: A cohort study. Palliative Medicine 2023, 37: 793-798. PMID: 36999898, DOI: 10.1177/02692163231162889.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnti-Bacterial AgentsCephalosporinsCohort StudiesDrug-Related Side Effects and Adverse ReactionsFemaleHumansMaleNeoplasmsConceptsAdverse drug eventsAntibiotic therapyDrug eventsAdvanced cancerOlder adultsIndex admissionPalliative chemotherapyCohort studyTertiary care centerHospitalized older adultsPalliative care providersMultidrug-resistant organismsMean ageCommon tumorsCare centerCare providersRatio of daysSolid tumorsMultivariable testingPatientsTherapyStandardized criteriaCancerMean timeAdults
2019
Perspectives on antimicrobial use at the end of life among antibiotic stewardship programs: A survey of the Society for Healthcare Epidemiology of America Research Network
Datta R, Topal J, McManus D, Dembry LM, Quagliarello V, Juthani-Mehta M. Perspectives on antimicrobial use at the end of life among antibiotic stewardship programs: A survey of the Society for Healthcare Epidemiology of America Research Network. Infection Control And Hospital Epidemiology 2019, 40: 1074-1076. PMID: 31328703, PMCID: PMC7165360, DOI: 10.1017/ice.2019.194.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsAntimicrobial StewardshipDrug Utilization ReviewHumansPatient ComfortSurveys and QuestionnairesTerminal CareUnited StatesIncreased Length of Stay Associated With Antibiotic Use in Older Adults With Advanced Cancer Transitioned to Comfort Measures
Datta R, Zhu M, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Increased Length of Stay Associated With Antibiotic Use in Older Adults With Advanced Cancer Transitioned to Comfort Measures. American Journal Of Hospice And Palliative Medicine® 2019, 37: 27-33. PMID: 31185722, PMCID: PMC6868290, DOI: 10.1177/1049909119855617.Peer-Reviewed Original ResearchConceptsAdvanced cancerAntibiotic useComfort measuresPoisson regression modelsInfection diagnosisIntensive care unit admissionMultivariable Poisson regression modelsCare unit admissionCohort of patientsUrinary tract infectionGoal-concordant careUnit admissionEnd of lifeHospital lengthOlder patientsTract infectionsLonger LOSMedian ageRegression modelsStay AssociatedAntibiotic exposureLiquid tumorsPatientsCancerCancer typesAntibiotic-sparing agents for uncomplicated cystitis: uva-ursi and ibuprofen not ready for primetime
Datta R, Juthani-Mehta M. Antibiotic-sparing agents for uncomplicated cystitis: uva-ursi and ibuprofen not ready for primetime. Clinical Microbiology And Infection 2019, 25: 922-924. PMID: 31035018, PMCID: PMC6612576, DOI: 10.1016/j.cmi.2019.04.022.Commentaries, Editorials and LettersAntimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures
Datta R, Wang T, Zhu M, Dembry LM, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. Infection Control And Hospital Epidemiology 2019, 40: 470-472. PMID: 30821230, PMCID: PMC6482377, DOI: 10.1017/ice.2019.22.Peer-Reviewed Original ResearchConceptsUrinary tract infectionIncidence rate ratiosAdvanced cancer patientsAsymptomatic bacteriuriaCancer patientsAntimicrobial therapySymptomatic urinary tract infectionPotential urinary tract infectionTract infectionsInappropriate therapyAntimicrobial daysComfort measuresBacteriuriaCandiduriaCFU/mLPatientsTherapyRate ratioMLInfection
2018
Uncomplicated Cystitis in Nursing Home Residents: A Practical Guide to Diagnosis and Management
Datta R, Juthani-Mehta M. Uncomplicated Cystitis in Nursing Home Residents: A Practical Guide to Diagnosis and Management. Journal Of The American Medical Directors Association 2018, 19: 733-735. PMID: 30149841, PMCID: PMC6510384, DOI: 10.1016/j.jamda.2018.07.015.Commentaries, Editorials and LettersMenace Elbow: Disseminated Nocardiosis
Datta R, Kramer E, Reinhart H, Campbell S, Wong E, Gupta S. Menace Elbow: Disseminated Nocardiosis. The American Journal Of Medicine 2018, 131: 1307-1309. PMID: 29729234, PMCID: PMC6482376, DOI: 10.1016/j.amjmed.2018.04.012.Peer-Reviewed Case Reports and Technical NotesNitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis
Datta R, Juthani-Mehta M. Nitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis. JAMA 2018, 319: 1771-1772. PMID: 29710273, PMCID: PMC6565436, DOI: 10.1001/jama.2018.4654.Commentaries, Editorials and Letters
2015
Quantifying the Exposure to Antibiotic-Resistant Pathogens Among Patients Discharged From a Single Hospital Across All California Healthcare Facilities
Datta R, Brown S, Nguyen VQ, Cao C, Billimek J, Avery T, Lee BY, Huang SS. Quantifying the Exposure to Antibiotic-Resistant Pathogens Among Patients Discharged From a Single Hospital Across All California Healthcare Facilities. Infection Control And Hospital Epidemiology 2015, 36: 1275-1282. PMID: 26387690, DOI: 10.1017/ice.2015.181.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsCaliforniaCarrier StateClostridiumCross InfectionDrug Resistance, BacterialFemaleHospitalsHumansKlebsiella pneumoniaeLength of StayMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedNursing HomesPatient DischargePatient ReadmissionRetrospective StudiesVancomycin-Resistant EnterococciYoung AdultConceptsMethicillin-resistant Staphylococcus aureusClostridium difficile infectionVancomycin-resistant enterococciNursing homesAntibiotic-resistant pathogensDays of dischargeHealthcare facilitiesLength of stayExtended-spectrum β-lactamaseYear of dischargeMultiple cohort studiesTime-dependent exposureESBL carriersMore readmissionsCDI patientsHospital readmissionDifficile infectionSingle hospitalReadmissionHospitalPatientsKlebsiella pneumoniaeΒ-lactamaseStaphylococcus aureusNoncarriers
2011
Colonization with antibiotic-susceptible strains protects against methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition: a nested case-control study
Huang SS, Datta R, Rifas-Shiman S, Kleinman K, Placzek H, Lankiewicz JD, Platt R. Colonization with antibiotic-susceptible strains protects against methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition: a nested case-control study. Critical Care 2011, 15: r210. PMID: 21914221, PMCID: PMC3334754, DOI: 10.1186/cc10445.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusMethicillin-sensitive Staphylococcus aureusVancomycin-resistant enterococciInitial negative swabCase-control studyVancomycin-sensitive enterococciMRSA acquisitionVRE acquisitionICU admissionRisk factorsNegative swabsStaphylococcus aureusHigh endemic settingMRSA-positive patientsVancomycin-resistant enterococci acquisitionThird-generation cephalosporinsSensitive strainsPredictors of acquisitionBilateral naresMSSA carriageMSSA infectionsSame hospitalizationICU patientsLow albuminMRSA infection