Confounding by indication affects antimicrobial risk factors for methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition
Datta R, Kleinman K, Rifas-Shiman S, Placzek H, Lankiewicz J, Platt R, Huang SS, for the CDC Prevention Epicenters. Confounding by indication affects antimicrobial risk factors for methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition. Antimicrobial Resistance & Infection Control 2014, 3: 19. PMID: 24932407, PMCID: PMC4057914, DOI: 10.1186/2047-2994-3-19.Peer-Reviewed Original ResearchMethicillin-resistant Staphylococcus aureusVancomycin-resistant enterococci acquisitionEmpiric antibioticsRisk factorsVRE acquisitionAntibiotic prescriptionsMRSA acquisitionScreening culturesIntensive care unit patientsAntibiotic utilization dataMRSA-positive patientsVRE-positive patientsCare unit patientsMedical record reviewDiagnosis of infectionEvidence of treatmentSymptoms of infectionStaphylococcus aureusBackgroundObservational studiesEmpiric therapyUnit patientsRecord reviewTreatment indicationsPrior historyLow prevalence