2024
Characterizing the progression of subclinical cardiac amyloidosis through artificial intelligence applied to electrocardiographic images and echocardiograms
Oikonomou E, Sangha V, Coppi A, Krumholz H, Miller E, Khera R. Characterizing the progression of subclinical cardiac amyloidosis through artificial intelligence applied to electrocardiographic images and echocardiograms. European Heart Journal 2024, 45: ehae666.2089. DOI: 10.1093/eurheartj/ehae666.2089.Peer-Reviewed Original ResearchDiagnosis of ATTR-CMATTR-CMBone scintigraphy scansClinical diagnosisTransthyretin amyloid cardiomyopathyMonths of diagnosisSex-matched controlsElectrocardiographic (ECGIndolent courseCardiac amyloidosisScintigraphy scanAmyloid cardiomyopathyEchocardiographic studiesAI-ECGEchocardiogramEventual diagnosisDetect longitudinal changesConfirmatory testDiagnosisClinical diseasePercentage of individualsLongitudinal changesECGMedianMonths
2021
Financial Hardship Among Nonelderly Adults With CKD in the United States
Acquah I, Valero-Elizondo J, Javed Z, Ibrahim HN, Patel KV, Ryoo Ali HJ, Menser T, Khera R, Cainzos-Achirica M, Nasir K. Financial Hardship Among Nonelderly Adults With CKD in the United States. American Journal Of Kidney Diseases 2021, 78: 658-668. PMID: 34144103, DOI: 10.1053/j.ajkd.2021.04.011.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseLack of insuranceMedical billsDiagnosis of CKDMultivariable logistic regression modelNational Health Interview SurveyHealth Interview SurveyFinancial hardshipLogistic regression modelsClinical characteristicsClinical factorsCKD diagnosisKidney diseaseUS populationAbstractTextStudy designInterview SurveyRepresentative estimatesDiagnosisRegression modelsRepresentative sampleAdultsOutcomesStrong determinantAMP
2015
Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism
Jain S, Khera R, Suneja M, Gehlbach B, Kuperman E, Lopez F. Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism. The American Journal Of The Medical Sciences 2015, 350: 501-507. PMID: 25719981, DOI: 10.1097/maj.0000000000000405.Peer-Reviewed Original ResearchConceptsDiagnosis of PEPulmonary embolismClinical featuresD-dimerDiagnostic algorithmPositive D-dimer testNonspecific clinical featuresSimple noninvasive testD-dimer testD-dimer assayClinician suspicionInitial imagingAlternative diagnosesElderly menNoninvasive testsClinical algorithmDiagnostic evaluationChest imagingDiagnosisEmbolismLittle valueImagingComorbiditiesPneumoniaPatients