1998
Conservation of T Cell Receptor Conformation in Epidermal γδ Cells with Disrupted Primary Vγ Gene Usage
Mallick-Wood C, Lewis J, Richie L, Owen M, Tigelaar R, Hayday A. Conservation of T Cell Receptor Conformation in Epidermal γδ Cells with Disrupted Primary Vγ Gene Usage. Science 1998, 279: 1729-1733. PMID: 9497293, DOI: 10.1126/science.279.5357.1729.Peer-Reviewed Original ResearchConceptsGene segmentsVariable region gene segmentsRegion gene segmentsParticular gene segmentsReceptor conformationTCR chainsReceptor gammaAssociation of expressionAlphabeta T cellsCellsConservationT-cell receptor gammaConformational determinantsGammadelta T cell subsetsGene usageT cellsConformationΓδ cellsB cellsLymphocyte repertoireVgamma5SitesDendritic epidermal T cellsExpressionRepertoire
1988
Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells
Asarnow D, Kuziel W, Bonyhad M, Tigelaar R, Tucker P, Allison J. Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells. Cell 1988, 55: 837-847. PMID: 2847872, DOI: 10.1016/0092-8674(88)90139-0.Peer-Reviewed Original ResearchConceptsT cellsGamma delta antigen receptorsDendritic epidermal cellsPeripheral lymphoid tissuesAdult T-cellEarly fetal thymusLymphoid tissueImmune surveillanceFetal thymusFetal thymocytesThy-1Antigen receptorCell clonesAlpha betaReceptor geneAntigen receptor genesMinor populationDelta gene segmentsReceptorsMajor populationCellsDelta geneStriking homogeneityGene segmentsCertain epithelia
1987
Delta is the Cx-gene product in the γ/δ antigen receptor of dendritic epidermal cells
Bonyhadi M, Weiss A, Tucker P, Tigelaar R, Allison J. Delta is the Cx-gene product in the γ/δ antigen receptor of dendritic epidermal cells. Nature 1987, 330: 574-576. PMID: 3500417, DOI: 10.1038/330574a0.Peer-Reviewed Original ResearchConceptsDendritic epidermal cellsDisulfide-linked heterodimerEpidermal cellsΔ chainsThy-1Constant region genesAntigen receptorNorthern blot analysisΓ-chainRelative molecular mass MrCx genesMost T cellsMurine Thy-1Dimeric receptorMessenger RNAGene segmentsEndoglycosidase treatmentT cellsBlot analysisCell linesOligosaccharide residues