1998
Conservation of T Cell Receptor Conformation in Epidermal γδ Cells with Disrupted Primary Vγ Gene Usage
Mallick-Wood C, Lewis J, Richie L, Owen M, Tigelaar R, Hayday A. Conservation of T Cell Receptor Conformation in Epidermal γδ Cells with Disrupted Primary Vγ Gene Usage. Science 1998, 279: 1729-1733. PMID: 9497293, DOI: 10.1126/science.279.5357.1729.Peer-Reviewed Original ResearchConceptsGene segmentsVariable region gene segmentsRegion gene segmentsParticular gene segmentsReceptor conformationTCR chainsReceptor gammaAssociation of expressionAlphabeta T cellsCellsConservationT-cell receptor gammaConformational determinantsGammadelta T cell subsetsGene usageT cellsConformationΓδ cellsB cellsLymphocyte repertoireVgamma5SitesDendritic epidermal T cellsExpressionRepertoire
1995
Immunobiology of Mouse Dendritic Epidermal T Cells: A Decade Later, Some Answers, But Still More Questions
Tigelaar R, Lewis J. Immunobiology of Mouse Dendritic Epidermal T Cells: A Decade Later, Some Answers, But Still More Questions. Journal Of Investigative Dermatology 1995, 105: s43-s49. DOI: 10.1038/jid.1995.9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDendritic epidermal T cellsEpidermal T cellsT cell receptorΓδ cellsT cellsMouse dendritic epidermal T-cellsMurine dendritic epidermal T cellsCutaneous immune surveillanceNormal human skinSelf antigensImmune surveillanceNormal miceActive hair growthAdult miceEpithelial sitesCutaneous physiologyReproductive tractTissue restrictionHair growthFunctional activityMiceSkinHuman skinReceptorsOverwhelming evidence
1994
Factors Involved in the Localization and Activation of Murine γδ Positive Dendritic Epidermal T Cells
Tigelaar R, Lewis J. Factors Involved in the Localization and Activation of Murine γδ Positive Dendritic Epidermal T Cells. NATO Science Series A: 1994, 39-55. DOI: 10.1007/978-1-4615-1861-7_4.Peer-Reviewed Original ResearchDendritic epidermal T cellsMouse dendritic epidermal T-cellsT cell receptorEpidermal T cellsNormal miceT cellsAdoptive transfer studiesIdentical T cell receptorsPeripheral lymphoid tissuesContact dermatitis reactionsActivation/proliferationEarly fetal thymocytesEarly fetal thymusCutaneous immunityΓδ cellsNeonatal periodSelf antigensLymphoid tissueDETC linesFetal thymusMorphologic equivalentDermatitis reactionsEpithelial sitesSitu proliferationAdult thymus
1992
Expression of mouse Tla region class I genes in tissue enriched for γδ cells
Eghtesady P, Brorson K, Cheroutre H, Tigelaar R, Hood L, Kronenberg M. Expression of mouse Tla region class I genes in tissue enriched for γδ cells. Immunogenetics 1992, 36: 377-388. PMID: 1388139, DOI: 10.1007/bf00218045.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalBase SequenceBlotting, NorthernDNA ProbesFetusGene ExpressionGenes, MHC Class IMiceMice, Inbred BALB CMice, Inbred C57BLMolecular Sequence DataMultigene FamilyPolymerase Chain ReactionReceptors, Antigen, T-Cell, gamma-deltaRepetitive Sequences, Nucleic AcidT-LymphocytesConceptsΓδ T cellsT cellsPolymerase chain reactionTla region genesClass IΓδ T lymphocytesPresentation of antigensThymus leukemia antigenMajor histocompatibility complexRegion gene productsΓδ cellsLeukemia antigenAntigen presentationT lymphocytesRegion genesFetal tissuesTL antigensMouse major histocompatibility complexMonoclonal antibodiesHistocompatibility complexPattern of expressionAntigenChain reactionRecent evidenceNorthern blot analysis