2020
Firearm-Related Injury and Death in the United States.
McLean R. Firearm-Related Injury and Death in the United States. Annals Of Internal Medicine 2020, 172: 368. PMID: 32120388, DOI: 10.7326/l19-0744.Peer-Reviewed Original ResearchThe U.S. Health Care System Is Ill and Needs a Bold New Prescription.
McLean R, DeLong D, Moyer D. The U.S. Health Care System Is Ill and Needs a Bold New Prescription. Annals Of Internal Medicine 2020, 172: s1-s2. PMID: 31958806, DOI: 10.7326/m19-3712.Peer-Reviewed Original ResearchTestosterone Treatment in Adult Men With Age-Related Low Testosterone: A Clinical Guideline From the American College of Physicians.
Qaseem A, Horwitch C, Vijan S, Etxeandia-Ikobaltzeta I, Kansagara D, Forciea M, Crandall C, Fitterman N, Hicks L, Lin J, Maroto M, McLean R, Mustafa R, Tufte J. Testosterone Treatment in Adult Men With Age-Related Low Testosterone: A Clinical Guideline From the American College of Physicians. Annals Of Internal Medicine 2020, 172: 126-133. PMID: 31905405, DOI: 10.7326/m19-0882.Peer-Reviewed Original ResearchConceptsLow testosteroneTestosterone treatmentSexual functionAdult menAdverse eventsPatient populationPhysical functionSexual dysfunctionAmerican CollegeACP Clinical Guidelines CommitteeMajor adverse cardiovascular eventsClinical Guidelines CommitteeAdverse cardiovascular eventsSerious adverse eventsTarget patient populationQuality of lifeCardiovascular eventsIntramuscular formulationClinical outcomesGuidelines CommitteeClinical effectivenessPatient preferencesClinical guidelinesClinical recommendationsFamily physicians
2019
Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians.
Qaseem A, Crandall C, Mustafa R, Hicks L, Wilt T, Forciea M, Fitterman N, Horwitch C, Kansagara D, Maroto M, McLean R, Roa J, Tufte J. Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians. Annals Of Internal Medicine 2019, 171: 643-654. PMID: 31683290, PMCID: PMC8152103, DOI: 10.7326/m19-0642.Peer-Reviewed Original ResearchConceptsAverage-risk adultsFecal immunochemical testingColorectal cancerGuidance statementsImmunochemical testingPatient populationGuaiac-based fecal occult blood testingAsymptomatic average-risk adultsFecal occult blood testingScreening testColorectal cancer screening testsGuidelines International Network libraryOccult blood testingCancer screening testsAGREE II instrumentNational Guideline ClearinghouseTarget patient populationQuality of guidelinesFlexible sigmoidoscopyGuideline updateBlood testingPatient preferencesAmerican CollegeNational guidelinesClinical practiceDisclosure of Interests and Management of Conflicts of Interest in Clinical Guidelines and Guidance Statements: Methods From the Clinical Guidelines Committee of the American College of Physicians.
Qaseem A, Wilt T, Forciea M, Kansagara D, Crandall C, Fitterman N, Hicks L, Horwitch C, Lin J, Maroto M, McLean R, Mustafa R, Roa J, Tufte J, Vijan S. Disclosure of Interests and Management of Conflicts of Interest in Clinical Guidelines and Guidance Statements: Methods From the Clinical Guidelines Committee of the American College of Physicians. Annals Of Internal Medicine 2019, 171: 354-361. PMID: 31426089, DOI: 10.7326/m18-3279.Peer-Reviewed Original ResearchFirearm-Related Injury and Death in the United States: A Call to Action From the Nation's Leading Physician and Public Health Professional Organizations.
McLean R, Harris P, Cullen J, Maier R, Yasuda K, Schwartz B, Benjamin G. Firearm-Related Injury and Death in the United States: A Call to Action From the Nation's Leading Physician and Public Health Professional Organizations. Annals Of Internal Medicine 2019, 171: 573-577. PMID: 31390463, DOI: 10.7326/m19-2441.Peer-Reviewed Original ResearchThe Development of Clinical Guidelines and Guidance Statements by the Clinical Guidelines Committee of the American College of Physicians: Update of Methods.
Qaseem A, Kansagara D, Lin J, Mustafa R, Wilt T, Forciea M, Crandall C, Fitterman N, Hicks L, Horwitch C, Maroto M, McLean R, Roa J, Tufte J, Vijan S. The Development of Clinical Guidelines and Guidance Statements by the Clinical Guidelines Committee of the American College of Physicians: Update of Methods. Annals Of Internal Medicine 2019, 170: 863-870. PMID: 31181568, DOI: 10.7326/m18-3290.Peer-Reviewed Original ResearchConceptsClinical Guidelines CommitteeClinical guidelinesGuidance statementsGuidelines CommitteeAmerican CollegeACP Clinical Guidelines CommitteeEvidence-based clinical guidelinesPatient comorbid conditionsValue of careComorbid conditionsPatient valuesGRADE methodsStandardized reporting formatUpdate of methodsPhysiciansFurther clarificationGuidelinesScreening for Breast Cancer in Average-Risk Women: A Guidance Statement From the American College of Physicians.
Qaseem A, Lin J, Mustafa R, Horwitch C, Wilt T, Forciea M, Fitterman N, Iorio A, Kansagara D, Maroto M, McLean R, Tufte J, Vijan S. Screening for Breast Cancer in Average-Risk Women: A Guidance Statement From the American College of Physicians. Annals Of Internal Medicine 2019, 170: 547-560. PMID: 30959525, DOI: 10.7326/m18-2147.Peer-Reviewed Original ResearchConceptsAverage-risk womenBreast cancerGuidance statementsPatient populationGuidelines International Network libraryClinical breast examinationAge 50 yearsAGREE II instrumentNational Guideline ClearinghouseTarget patient populationBreast cancer screeningQuality of guidelinesAsymptomatic womenBiennial mammographyBreast examinationCancer screeningAmerican CollegeNational guidelinesMost womenClinical practiceCancerCliniciansAverage riskWomenLife expectancy
2018
World Health Organization Guidelines on Medicines for Diabetes Treatment Intensification: Commentary From the American College of Physicians High Value Care Committee.
Humphrey L, Kansagara D, Qaseem A, Centor R, DeLong D, Gantzer H, Horwitch C, Jokela J, Li J, Lohr R, López A, McLean R. World Health Organization Guidelines on Medicines for Diabetes Treatment Intensification: Commentary From the American College of Physicians High Value Care Committee. Annals Of Internal Medicine 2018, 169: 398-400. PMID: 30178054, DOI: 10.7326/m18-1148.Peer-Reviewed Original ResearchHemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians.
Qaseem A, Wilt T, Kansagara D, Horwitch C, Barry M, Forciea M, Fitterman N, Balzer K, Boyd C, Humphrey L, Iorio A, Lin J, Maroto M, McLean R, Mustafa R, Tufte J. Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians. Annals Of Internal Medicine 2018, 168: 569-576. PMID: 29507945, DOI: 10.7326/m17-0939.Peer-Reviewed Original ResearchConceptsType 2 diabetesAmerican CollegePharmacologic therapyGlycemic controlGeneral healthScottish Intercollegiate Guidelines NetworkGuidelines International Network libraryClinical Systems ImprovementHemoglobin A1c targetPatient's general healthAmerican Diabetes AssociationAGREE II instrumentLife expectancyNational Guideline ClearinghouseCost of careA1C targetsNonpregnant adultsMost patientsPharmacologic treatmentClinical EndocrinologistsTreatment burdenDiabetes AssociationPatient preferencesChronic conditionsAdvanced age
2017
Hepatitis B Vaccination, Screening, and Linkage to Care: Best Practice Advice From the American College of Physicians and the Centers for Disease Control and Prevention.
Abara W, Qaseem A, Schillie S, McMahon B, Harris A, Abraham G, Centor R, DeLong D, Gantzer H, Horwitch C, Humphrey L, Jokela J, Li J, Lohr R, López A, McLean R. Hepatitis B Vaccination, Screening, and Linkage to Care: Best Practice Advice From the American College of Physicians and the Centers for Disease Control and Prevention. Annals Of Internal Medicine 2017, 167: 794-804. PMID: 29159414, DOI: 10.7326/m17-1106.Peer-Reviewed Original ResearchConceptsHepatitis B virusHepatitis B vaccinationEnd-stage renal diseaseB vaccinationRenal diseaseAmerican CollegeChronic hepatitis B virus infectionElevated alanine aminotransferase levelsHepatitis B virus infectionDisease controlAlanine aminotransferase levelsB virus infectionChronic liver diseaseHigh HBV prevalenceHBV endemic regionsHIV-positive personsHigh-risk personsHepatitis C virusBest practice statementsPublic safety workersCare Task ForceBest Practice AdviceHBV prevalenceUnvaccinated adultsHBV infectionManagement of Acute and Recurrent Gout.
Harris R, McLean R, Qaseem A. Management of Acute and Recurrent Gout. Annals Of Internal Medicine 2017, 166: 760. PMID: 28505649, DOI: 10.7326/l17-0146.Peer-Reviewed Original ResearchTreatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update From the American College of Physicians.
Qaseem A, Forciea M, McLean R, Denberg T, Barry M, Cooke M, Fitterman N, Harris R, Humphrey L, Kansagara D, McLean R, Mir T, Schünemann H. Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update From the American College of Physicians. Annals Of Internal Medicine 2017, 166: 818-839. PMID: 28492856, DOI: 10.7326/m15-1361.Peer-Reviewed Original ResearchConceptsLow bone densityBone densityPharmacologic treatmentVertebral fracturesPatient populationAmerican CollegeSystematic reviewACP Clinical Guidelines CommitteeClinical Practice Guideline UpdateLong-term pharmacologic treatmentBone density monitoringClinical Guidelines CommitteeFracture risk profileWomen 65 yearsMenopausal estrogen therapyCost of medicationsLarge observational studiesTreatment of osteoporosisTarget patient populationProgestogen therapyEstrogen therapyAdverse eventsPharmacologic therapyOsteoporotic womenPhysician recommendationNoninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians.
Qaseem A, Wilt T, McLean R, Forciea M, Denberg T, Barry M, Boyd C, Chow R, Fitterman N, Harris R, Humphrey L, Vijan S. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Annals Of Internal Medicine 2017, 166: 514-530. PMID: 28192789, DOI: 10.7326/m16-2367.Peer-Reviewed Original ResearchConceptsChronic low back painLow back painNonsteroidal anti-inflammatory drugsBack painAnti-inflammatory drugsNonpharmacologic treatmentsPharmacologic treatmentPatient populationSpinal manipulationAmerican CollegeNoninvasive treatmentSystematic reviewLow-level laser therapySecond-line therapyBack pain episodesFirst-line therapyHealth-related qualityMotor control exercisesClinical practice guidelinesTarget patient populationSkeletal muscle relaxantsMindfulness-based stress reductionCognitive behavioral therapyNonpharmacologic therapiesPain episodesPharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From the American College of Physicians and the American Academy of Family Physicians.
Qaseem A, Wilt T, Rich R, Humphrey L, Frost J, Forciea M, Fitterman N, Barry M, Horwitch C, Iorio A, McLean R. Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From the American College of Physicians and the American Academy of Family Physicians. Annals Of Internal Medicine 2017, 166: 430-437. PMID: 28135725, DOI: 10.7326/m16-1785.Peer-Reviewed Original ResearchConceptsSpecific blood pressure targetsBlood pressure targetsTarget systolic blood pressureSystolic blood pressureLower blood pressure targetsPressure targetsBlood pressureCardiac eventsPharmacologic treatmentTreatment goalsPatient populationAmerican CollegeFamily physiciansAmerican AcademyAdults Aged 60 YearsHigh cardiovascular riskTransient ischemic attackMajor cardiac eventsHistory of strokeClinical practice guidelinesTreatment of hypertensionTarget patient populationIschemic attackRecurrent strokeCause mortalityOral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline Update From the American College of Physicians.
Qaseem A, Barry M, Humphrey L, Forciea M, Fitterman N, Horwitch C, Kansagara D, McLean R, Wilt T. Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline Update From the American College of Physicians. Annals Of Internal Medicine 2017, 166: 279-290. PMID: 28055075, DOI: 10.7326/m16-1860.Peer-Reviewed Original ResearchConceptsType 2 diabetesOral pharmacologic treatmentGlycemic controlPharmacologic treatmentPatient populationAmerican CollegeSodium-glucose cotransporter 2 inhibitorsType 2Clinical Practice Guideline UpdateDipeptidyl peptidase-4 inhibitorsCotransporter 2 inhibitorsSGLT-2 inhibitorsSystolic blood pressurePeptidase-4 inhibitorsDPP-4 inhibitorsTarget patient populationTotality of evidenceACP guidelinesCerebrovascular morbidityCause mortalityOral medicationsOral therapyPharmacologic therapyBlood pressureHemoglobin A1c
2016
Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians.
Qaseem A, McLean R, Starkey M, Forciea M, Denberg T, Barry M, Boyd C, Chow R, Fitterman N, Humphrey L, Kansagara D, Manaker S, Vijan S, Wilt T. Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians. Annals Of Internal Medicine 2016, 166: 52-57. PMID: 27802479, DOI: 10.7326/m16-0569.Peer-Reviewed Original ResearchConceptsAcute goutPatient populationAmerican CollegeShort-term clinical outcomesClinical practice guidelinesSynovial fluid analysisTarget patient populationDiagnosis of goutJoint swellingJoint inflammationClinical outcomesDatabase inceptionClinical recommendationsPractice guidelinesGout diagnosisEvaluated outcomesClinical judgmentGRADE methodsSystematic reviewClinical decisionDiagnostic testingGrading systemFluid analysisIntermediate outcomesAdverse effects
2010
An internist's commentary.
McLean R. An internist's commentary. Connecticut Medicine 2010, 74: 293-4. PMID: 20514715.Peer-Reviewed Original Research