2016
Determination of a Testing Threshold for Lumbar Puncture in the Diagnosis of Subarachnoid Hemorrhage after a Negative Head Computed Tomography: A Decision Analysis
Taylor RA, Gill H, Marcolini EG, Meyers HP, Faust JS, Newman DH. Determination of a Testing Threshold for Lumbar Puncture in the Diagnosis of Subarachnoid Hemorrhage after a Negative Head Computed Tomography: A Decision Analysis. Academic Emergency Medicine 2016, 23: 1119-1127. PMID: 27378053, DOI: 10.1111/acem.13042.Peer-Reviewed Original ResearchConceptsProbabilistic sensitivity analysesNegative head CTAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageLumbar punctureNegative CTTesting thresholdHead CTNormal neurologic findingsContrast-induced nephropathyNonaneurysmal subarachnoid hemorrhageLong-term morbidityHead Computed TomographyTwo-way sensitivity analysesDecision analytic modelProbability of deathNeurologic findingsRenal failureClinical variablesCurrent guidelinesPretest probabilityComputed tomographySecondary aimCTHemorrhage
2013
A decision analysis to determine a testing threshold for computed tomographic angiography and d-dimer in the evaluation of aortic dissection
Taylor RA, Iyer NS. A decision analysis to determine a testing threshold for computed tomographic angiography and d-dimer in the evaluation of aortic dissection. The American Journal Of Emergency Medicine 2013, 31: 1047-1055. PMID: 23702073, DOI: 10.1016/j.ajem.2013.03.039.Peer-Reviewed Original ResearchConceptsThoracic aortic dissectionD-dimerTesting thresholdAortic dissectionTomographic angiographyAcute renal failureHigh-risk featuresRenal replacement therapyClinical decision ruleD-dimer testingD-dimer sensitivityD-dimer testLarge mortality benefitMortality benefitPatient ageRenal failureReplacement therapyPretest probabilityLow prevalenceCTA testSmall riskDecision analysis softwareDisease probabilityCTAAngiography