2009
HOXA11 Promotes Fibroblast Proliferation and Regulates p53 in Uterosacral Ligaments
Connell KA, Guess MK, Chen HW, Lynch T, Bercik R, Taylor HS. HOXA11 Promotes Fibroblast Proliferation and Regulates p53 in Uterosacral Ligaments. Reproductive Sciences 2009, 16: 694-700. PMID: 19372592, PMCID: PMC3107841, DOI: 10.1177/1933719109334260.Peer-Reviewed Original ResearchConceptsCell proliferationExtracellular matrix proteinsTumor suppressor geneECM genesExpression of HOXA11Cell cycleMatrix proteinsSuppressor geneMurine fibroblastsRegulate p53Phenotypic abnormalitiesGenesHOXA11Rate of proliferationHOXA11 expressionExpressionP53ProliferationExpression of p53Fibroblast proliferationKey support structuresProteinHomeostasisDevelopment of POPBetter understanding
2008
HOXA11 is critical for development and maintenance of uterosacral ligaments and deficient in pelvic prolapse
Connell KA, Guess MK, Chen H, Andikyan V, Bercik R, Taylor HS. HOXA11 is critical for development and maintenance of uterosacral ligaments and deficient in pelvic prolapse. Journal Of Clinical Investigation 2008, 118: 1050-1055. PMID: 18274672, PMCID: PMC2242622, DOI: 10.1172/jci34193.Peer-Reviewed Original Research