Is it safe to stop oral anticoagulation after catheter ablation for atrial fibrillation?
Romero J, Avendano R, Diaz J, Taveras J, Lupercio F, Di Biase L. Is it safe to stop oral anticoagulation after catheter ablation for atrial fibrillation? Expert Review Of Cardiovascular Therapy 2018, 17: 31-41. PMID: 30460874, DOI: 10.1080/14779072.2019.1550718.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAnticoagulantsAtrial FibrillationCatheter AblationHemorrhageHumansPrevalenceStrokeTreatment OutcomeWithholding TreatmentConceptsCatheter ablationAtrial fibrillationOral anticoagulantsOral anticoagulationBlanking periodRisk of bleedingSociety guidelinesCommon arrhythmiaCurrent guidelinesFibrillationAnticoagulantsRelevant articlesMajor databasesAnticoagulationAblationRiskGuidelinesBleedingEMBASEArrhythmiasPubMedStrokeMajor recommendationsPrevalenceClinical outcomes in patients with atrial fibrillation receiving amiodarone on NOACs vs. warfarin
Avendano R, Romero J, Lupercio F, Diaz J, Quispe R, Golive A, Natale A, Garcia M, Krumerman A, Di Biase L. Clinical outcomes in patients with atrial fibrillation receiving amiodarone on NOACs vs. warfarin. Journal Of Interventional Cardiac Electrophysiology 2018, 54: 73-80. PMID: 30128801, DOI: 10.1007/s10840-018-0427-y.Peer-Reviewed Original ResearchConceptsNew oral anticoagulantsMajor bleedingAtrial fibrillationThromboembolic eventsIntracranial bleedingClinical outcomesRisk ratioStroke/thromboembolic eventsRecent retrospective trialsMantel-Haenszel methodConclusionAmong patientsTE preventionOral anticoagulantsIncreased riskRetrospective trialsResultsA totalHigh riskAmiodaroneBleedingPatientsWarfarinSystematic reviewP-glycoproteinConfidence intervalsOutcomesUninterrupted direct oral anticoagulants vs. uninterrupted vitamin K antagonists during catheter ablation of non-valvular atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials
Romero J, Cerrud-Rodriguez R, Diaz J, Michaud G, Taveras J, Alviz I, Grupposo V, Cerna L, Avendano R, Kumar S, Kirchhof P, Natale A, Di Biase L. Uninterrupted direct oral anticoagulants vs. uninterrupted vitamin K antagonists during catheter ablation of non-valvular atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials. EP Europace 2018, 20: 1612-1620. PMID: 29982383, DOI: 10.1093/europace/euy133.Peer-Reviewed Original ResearchConceptsNon-valvular atrial fibrillationUninterrupted direct oral anticoagulantsUninterrupted vitamin K antagonistsDirect oral anticoagulantsVitamin K antagonistsMajor bleeding eventsSilent cerebral infarctionThrombo-embolic eventsCatheter ablationBleeding eventsAtrial fibrillationMajor bleedingK antagonistsOral anticoagulantsSystematic reviewBrain magnetic resonance imagingMinor bleeding eventsFirst-line therapyParoxysmal atrial fibrillationRandom-effects modelMagnetic resonance imagingFixed-effects modelMinor bleedingCerebral infarctionLine therapyBenefit of left atrial appendage electrical isolation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis
Romero J, Michaud G, Avendano R, Briceño D, Kumar S, Diaz J, Mohanty S, Trivedi C, Gianni C, Della Rocca D, Proietti R, Perrotta L, Bordignon S, Chun J, Schmidt B, Garcia M, Natale A, Di Biase L. Benefit of left atrial appendage electrical isolation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis. EP Europace 2018, 20: 1268-1278. PMID: 29342299, DOI: 10.1093/europace/eux372.Peer-Reviewed Original ResearchConceptsAtrial appendage electrical isolationPersistent atrial fibrillationAtrial fibrillationIschemic strokeSystematic reviewNon-paroxysmal AF patientsStandard ablationNon-paroxysmal atrial fibrillationAcute procedural complicationsIncremental benefitAcute complication rateLong-term outcomesAntiarrhythmic medicationsArrhythmia recurrenceComplication rateAF patientsProcedural complicationsCatheter ablationAtrial arrhythmiasClinical studiesOverall freedomLAAEIPatientsLSPAFFibrillation