2018
Physical training reverses changes in hepatic mitochondrial diameter of Alloxan-induced diabetic rats
Kuga G, Gaspar R, Muñoz V, Nakandakari S, Breda L, Sandoval B, Caetano F, de Almeida Leme J, Pauli J, Gomes R. Physical training reverses changes in hepatic mitochondrial diameter of Alloxan-induced diabetic rats. Einstein (São Paulo) 2018, 16: eao4353. PMID: 30088548, PMCID: PMC6110382, DOI: 10.1590/s1679-45082018ao4353.Peer-Reviewed Original ResearchConceptsDiabetic ratsBody weightDiabetic groupSedentary diabeticDiabetic animalsPhysical trainingSedentary diabetic animalsPhysical training protocolMitochondrial diameterDiabetes mellitusAlloxan administrationBlood insulinExercise protocolSerum glucoseSedentary controlsWistar ratsHepatic metabolismReverses changesLiver glycogenHepatic glycogenDiabeticsRatsMeasurements of glycogenLiver samplesTraining protocol
2017
Physical exercise reduces pyruvate carboxylase (PCB) and contributes to hyperglycemia reduction in obese mice
Muñoz V, Gaspar R, Crisol B, Formigari G, Sant’Ana M, Botezelli J, Gaspar R, da Silva A, Cintra D, de Moura L, Ropelle E, Pauli J. Physical exercise reduces pyruvate carboxylase (PCB) and contributes to hyperglycemia reduction in obese mice. The Journal Of Physiological Sciences 2017, 68: 493-501. PMID: 28710665, PMCID: PMC10717866, DOI: 10.1007/s12576-017-0559-3.Peer-Reviewed Original ResearchConceptsDiet-induced obesityObesity-inducing dietInsulin tolerance testObese micePhysical exerciseDIO miceExercise trainingControl miceHepatic tissueStandard rodent chowDevelopment of hyperglycemiaExercise training protocolType 2 diabetesTreadmill running protocolPhysical exercise sessionGlucose homeostasis controlEXE miceHyperglycemia reductionObese conditionsRodent chowTolerance testSerum glucoseSwiss miceExercise sessionsEpididymal fat