2009
Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators
Lampert R, Shusterman V, Burg M, McPherson C, Batsford W, Goldberg A, Soufer R. Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators. Journal Of The American College Of Cardiology 2009, 53: 774-778. PMID: 19245968, PMCID: PMC3979284, DOI: 10.1016/j.jacc.2008.10.053.Peer-Reviewed Original ResearchConceptsVentricular tachycardia/ventricular fibrillationFuture ventricular arrhythmiasT-wave alternansVentricular arrhythmiasVentricular fibrillationSpontaneous ventricular tachycardia/ventricular fibrillationHigher TWAImplantable cardioverter defibrillatorEjection fractionHighest quartileTWA testingWide QRSClinical arrhythmiaAmbulatory electrocardiographyLowest quartileFuture arrhythmiasSudden deathCardioverter defibrillatorClinical roleMultivariable regressionPatientsArrhythmiasRepolarization instabilityStress protocolSignificant predictors
2007
Implantable Cardioverter‐Defibrillator Shocks Increase T‐Wave Alternans
LAMPERT R, SOUFER R, McPHERSON CA, BATSFORD WP, TIRADO S, EARLEY C, GOLDBERG A, SHUSTERMAN V. Implantable Cardioverter‐Defibrillator Shocks Increase T‐Wave Alternans. Journal Of Cardiovascular Electrophysiology 2007, 18: 512-517. PMID: 17428273, DOI: 10.1111/j.1540-8167.2007.00787.x.Peer-Reviewed Original ResearchMeSH KeywordsDefibrillators, ImplantableElectric CountershockElectrocardiography, AmbulatoryFemaleHeart FailureHumansMaleMiddle AgedRisk AssessmentRisk FactorsVentricular FibrillationConceptsRepolarization instabilityQRS duration changesImplantable defibrillator shocksAmbulatory ECG monitoringT-wave alternansNorepinephrine levelsCoronary diseaseICD shocksSympathetic stimulationVentricular arrhythmiasInduced arrhythmiasVentricular arrhythmogenesisDefibrillator shocksQRS durationQT intervalSedated stateAdequate preClinical implicationsDefibrillation therapyECG monitoringRR intervalsHolter dataBaseline statePatientsArrhythmias
2006
Electrophysiologic characteristics of anger-triggered arrhythmias
Stopper M, Joska T, Burg MM, Batsford WP, McPherson CA, Jain D, Lampert R. Electrophysiologic characteristics of anger-triggered arrhythmias. Heart Rhythm 2006, 4: 268-273. PMID: 17341385, DOI: 10.1016/j.hrthm.2006.11.003.Peer-Reviewed Original ResearchConceptsVentricular arrhythmiasElectrophysiologic characteristicsPolymorphic ventricular tachycardiaMood statesDisorganized rhythmInitial therapyAppropriate shocksVentricular tachycardiaArrhythmogenic substrateSudden deathArrhythmiasPatientsIntracardiac electrogramsElectrogramsPossible mechanismTime of shockInitiation patternsTachycardiaTherapyInitiationICD
2005
Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators Results from the Triggers of Ventricular Arrhythmias (TOVA) study
Whang W, Albert CM, Sears SF, Lampert R, Conti JB, Wang PJ, Singh JP, Ruskin JN, Muller JE, Mittleman MA, Investigators T. Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators Results from the Triggers of Ventricular Arrhythmias (TOVA) study. Journal Of The American College Of Cardiology 2005, 45: 1090-1095. PMID: 15808769, DOI: 10.1016/j.jacc.2004.12.053.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseVT/VFSymptoms of depressionVentricular arrhythmiasSevere depressionAnderson-Gill proportional hazards modelsArrhythmia studiesImplantable cardioverter defibrillator patientsEpidemiologic Studies Depression ScaleCardioverter-defibrillator patientsFatal ventricular arrhythmiasProportional hazards modelRisk of shockCAD patientsFirst shockAppropriate shocksArtery diseaseICD dischargesICD patientsRecurrent episodesMultiple confoundersElevated riskSevere symptomsDepression severityHazards model