2021
Novel RNA Interference (RNAi)-Based Nanomedicines for Treating Viral Infections
Maes N, Zeller S, Kumar P. Novel RNA Interference (RNAi)-Based Nanomedicines for Treating Viral Infections. 2021, 223-264. DOI: 10.1201/9781003125259-8.Peer-Reviewed Original ResearchJapanese encephalitis virusNon-target tissuesHuman papillomavirusPediatric encephalitisTherapeutic modalitiesMajor safety concernNovel RNA interferenceViral infectionReplication-competent lentivirusClinical testingEncephalitis virusInfectious diseasesMajor causeSafety concernsDiseaseVector mobilizationRibonucleic acid interferenceTarget effectsRNA interferenceTargets of microRNAsEncephalitisPapillomavirusVaccineInfectionFlaviviruses
2016
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary
Akkina R, Allam A, Balazs AB, Blankson JN, Burnett JC, Casares S, Garcia JV, Hasenkrug KJ, Kashanchi F, Kitchen SG, Klein F, Kumar P, Luster AD, Poluektova LY, Rao M, Sanders-Beer BE, Shultz LD, Zack JA. Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary. AIDS Research And Human Retroviruses 2016, 32: 109-119. PMID: 26670361, PMCID: PMC4761823, DOI: 10.1089/aid.2015.0258.Peer-Reviewed Original ResearchConceptsHuman leukocyte antigenHumanized mouse modelHuman immunodeficiency virusMouse modelCell engraftmentHuman hematopoietic cell engraftmentNIH/NIAIDHIV immune responsesImmunodeficient mouse strainsHematopoietic cell engraftmentHuman T cellsHIV reservoirXenogeneic graftImmunodeficiency syndromeHumanized miceImmunodeficiency virusLymphoid structuresLeukocyte antigenNew imaging techniquesT cellsImmune responseImmunodeficient miceHost responseHIV researchInfectious diseases