1992
The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2
Brownstein D, Smith A, Johnson E, Pintel D, Naeger L, Tattersall P. The pathogenesis of infection with minute virus of mice depends on expression of the small nonstructural protein NS2 and on the genotype of the allotropic determinants VP1 and VP2. Journal Of Virology 1992, 66: 3118-3124. PMID: 1373202, PMCID: PMC241074, DOI: 10.1128/jvi.66.5.3118-3124.1992.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCapsidDNA, ViralEpitopesGenetic VariationImmunohistochemistryMiceMice, Inbred C3HMinute virus of miceMutagenesisNucleic Acid HybridizationParvoviridae InfectionsStructure-Activity RelationshipTissue DistributionViral Core ProteinsViral Nonstructural ProteinsVirulenceConceptsPathogenesis of infectionAsymptomatic infectionMultiple organsViral capsid antigenMesenteric lymph nodesSmooth muscle cellsSame target cellsMVMi infectionLymph nodesCapsid antigenMVMp infectionLethal infectionC3H/Lymphoid cellsTarget organsSimilar dosesAllotropic determinantMinute virusInfectious virusVirus titrationInfectionMuscle cellsMiceTitersTarget cells
1991
Pathogenesis of infection with a virulent allotropic variant of minute virus of mice and regulation by host genotype.
Brownstein D, Smith A, Jacoby R, Johnson E, Hansen G, Tattersall P. Pathogenesis of infection with a virulent allotropic variant of minute virus of mice and regulation by host genotype. Laboratory Investigation 1991, 65: 357-64. PMID: 1653878.Peer-Reviewed Original ResearchConceptsViral capsid antigenH miceInfectious virus titersB6 miceMVMi infectionCapsid antigenLethal infectionVirus titersPathogenesis of infectionBALB/cStrains of miceMinute virusAccelerated involutionSitu hybridizationC57BL/6 miceAsymptomatic infectionIntestinal hemorrhageNeonatal micePapillary hemorrhageDBA/2 miceC3H miceTarget organsVirus titrationVirus replicationGenetic susceptibility