2010
Robot-Assisted Therapy for Long-Term Upper-Limb Impairment after Stroke
Lo AC, Guarino PD, Richards LG, Haselkorn JK, Wittenberg GF, Federman DG, Ringer RJ, Wagner TH, Krebs HI, Volpe BT, Bever CT, Bravata DM, Duncan PW, Corn BH, Maffucci AD, Nadeau SE, Conroy SS, Powell JM, Huang GD, Peduzzi P. Robot-Assisted Therapy for Long-Term Upper-Limb Impairment after Stroke. New England Journal Of Medicine 2010, 362: 1772-1783. PMID: 20400552, PMCID: PMC5592692, DOI: 10.1056/nejmoa0911341.Peer-Reviewed Original ResearchConceptsWolf Motor Function TestFugl-Meyer scoreUsual careMotor Function TestRobot-assisted therapyStroke Impact ScaleIntensive therapySecondary analysisFunction testsComparison therapyMotor functionImpact ScaleSerious adverse eventsFugl-Meyer AssessmentUpper limb deficitsLong-term deficitsSensorimotor recoveryAdverse eventsSecondary outcomesPrimary outcomeRehabilitative therapyPatientsLimb impairmentTherapyStroke
2006
Consumer involvement in consent document development: a multicenter cluster randomized trial to assess study participants' understanding
Guarino P, Elbourne D, Carpenter J, Peduzzi P. Consumer involvement in consent document development: a multicenter cluster randomized trial to assess study participants' understanding. Clinical Trials 2006, 3: 19-30. PMID: 16539087, DOI: 10.1191/1740774506cn133oa.Peer-Reviewed Original ResearchMeSH KeywordsAdultCommunity ParticipationComprehensionConsent FormsFemaleHumansLeast-Squares AnalysisMaleProgram DevelopmentResearch SubjectsSurveys and QuestionnairesConceptsGulf War veterans' illnessesStudy participantsClient Satisfaction Questionnaire-8Outcome assessment questionnaireProportion of patientsPrimary outcome measureMean treatment differenceUS medical centersConsent documentsSignificant differencesPotential study participantsSecondary outcomesAdherence ratesTrial protocolClinical trialsMulticenter clusterOutcome measuresMedical CenterStudy investigatorsAssessment QuestionnaireStudy refusalThree monthsTrial initiationClinical researchInformed consent