Low-Grade Astrocytoma within a Mature Cystic Teratoma in an Adolescent Patient
Yoder N, Marks A, Hui P, Litkouhi B, Cron J. Low-Grade Astrocytoma within a Mature Cystic Teratoma in an Adolescent Patient. Journal Of Pediatric And Adolescent Gynecology 2017, 31: 325-327. PMID: 29107097, DOI: 10.1016/j.jpag.2017.10.005.Peer-Reviewed Original ResearchConceptsMature cystic teratomaCystic teratomaLow-grade astrocytomasAdolescent patientsMalignant transformationAsymptomatic ovarian cystsCommon ovarian neoplasmsLarger tumor sizeGynecologic tractSubsequent cystectomyPostmenopausal statusFinal pathologyOvarian neoplasmsOvarian cystsTumor sizeRisk factorsGlial tissueGrade astrocytomasAntigen 125Mouse modelSolid tumorsPatientsAstrocytomasTeratomaTrisomy 20Frequent homozygosity in both mature and immature ovarian teratomas: a shared genetic basis of tumorigenesis
Snir OL, DeJoseph M, Wong S, Buza N, Hui P. Frequent homozygosity in both mature and immature ovarian teratomas: a shared genetic basis of tumorigenesis. Modern Pathology 2017, 30: 1467-1475. PMID: 28664933, DOI: 10.1038/modpathol.2017.66.Peer-Reviewed Original ResearchConceptsMixed germ cell tumorGerm cell tumorsPure immature teratomaImmature teratomaCell tumorsMature teratomaGenetic zygosityMixed ovarian germ cell tumorOvarian germ cell tumorsOvarian immature teratomaImmature ovarian teratomaDifferent pathogenetic pathwaysMature cystic teratomaImmature teratoma componentsDifferent biological behaviorTeratoma componentsRate of homozygosityCystic teratomaOvarian teratomaTumor recurrenceCommon cellular originPathogenetic pathwaysGrade 2TumorsTeratoma