2009
Peace of Mind and Sense of Purpose as Core Existential Issues Among Parents of Children With Cancer
Mack JW, Wolfe J, Cook EF, Grier HE, Cleary PD, Weeks JC. Peace of Mind and Sense of Purpose as Core Existential Issues Among Parents of Children With Cancer. JAMA Pediatrics 2009, 163: 519-524. PMID: 19487607, DOI: 10.1001/archpediatrics.2009.57.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentBostonChildChild, PreschoolCommunicationCross-Sectional StudiesCultureData CollectionExistentialismHospitals, PediatricHumansInfantMotivationNeoplasmsParentsPersonality InventoryProfessional-Family RelationsPrognosisPsychometricsQuality of LifeSpiritualityTrustConceptsChronic Illness Therapy-Spiritual WellParents of childrenPrognostic informationFunctional assessmentDana-Farber Cancer InstituteMultivariable logistic regression modelCross-sectional surveyDetailed prognostic informationLogistic regression modelsOncologist judgmentChildren's HospitalMAIN OUTCOMECancer InstituteCancerCancer treatmentPeace of mindOncologistsHospitalScoresChildrenFirst yearHigh peaceRegression modelsMedical informationSubscale responses
2008
Perceptions of cancer‐related information among cancer survivors: A report from the American Cancer Society's Studies of Cancer Survivors
McInnes DK, Cleary PD, Stein KD, Ding L, Mehta CC, Ayanian JZ. Perceptions of cancer‐related information among cancer survivors: A report from the American Cancer Society's Studies of Cancer Survivors. Cancer 2008, 113: 1471-1479. PMID: 18666212, DOI: 10.1002/cncr.23713.Peer-Reviewed Original ResearchConceptsCancer survivorsCancer-related informationCancer informationCancer careLong-term side effectsAmerican Cancer Society's StudyCancer support groupsLow incomeSurvivors 3Cancer patientsCancer physiciansCommon cancerOlder womenSide effectsHealth outcomesYoung womenSurvivorsMental healthSupport groupsHealth informationCareWomenMore barriersUnfavorable ratingsPhysicians
2007
Hope and Prognostic Disclosure
Mack JW, Wolfe J, Cook EF, Grier HE, Cleary PD, Weeks JC. Hope and Prognostic Disclosure. Journal Of Clinical Oncology 2007, 25: 5636-5642. PMID: 18065734, DOI: 10.1200/jco.2007.12.6110.Peer-Reviewed Original ResearchConceptsPrognostic disclosurePrognostic informationPhysician communicationDana-Farber Cancer InstituteDisclosure of prognosisHalf of parentsChildren's HospitalParents of childrenChild's physicianMultivariable modelMAIN OUTCOMEParental recallCancer InstituteChild's oncologistChildren's CancerPatients' hopePhysiciansCancerEmotional distressPrognosisOncologistsHospitalChildren's likelihoodFirst yearCure
2005
Pain, Medication Use, and Health-Related Quality of Life in Older Persons With Postherpetic Neuralgia: Results From a Population-Based Survey
Oster G, Harding G, Dukes E, Edelsberg J, Cleary PD. Pain, Medication Use, and Health-Related Quality of Life in Older Persons With Postherpetic Neuralgia: Results From a Population-Based Survey. Journal Of Pain 2005, 6: 356-363. PMID: 15943957, DOI: 10.1016/j.jpain.2005.01.359.Peer-Reviewed Original ResearchConceptsHealth-related qualityPoor health-related qualityPostherpetic neuralgiaOlder personsPain interferenceUse of medicationsHealth index scoresYears of ageQuality of lifeMedication usePain intensityEnjoyment of lifeSubstantial painCurrent painPrescription medicationsMean durationPainIndex scoreOverall healthPrior weekNeuralgiaMedicationsGeneral activityHealthPersons
2004
Differences in Health-Related Quality of Life and Treatment Preferences Among Black and White Patients with End-Stage Renal Disease
Hicks LS, Cleary PD, Epstein AM, Ayanian JZ. Differences in Health-Related Quality of Life and Treatment Preferences Among Black and White Patients with End-Stage Renal Disease. Quality Of Life Research 2004, 13: 1129-1138. PMID: 15287279, DOI: 10.1023/b:qure.0000031350.56924.cc.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseRenal transplantationPhysical activityRenal diseaseWhite patientsEffect of ESRDOverall healthWhite womenWhite menHealth-related qualityMeasures of HRQLRacial differencesBetter overall healthQuality of lifeBlack womenBlack menBetter HRQLClinical characteristicsBlack patientsHRQL measuresPotential confoundersPatient preferencesTreatment preferencesPatientsAge 18Physicians’ beliefs about racial differences in referral for renal transplantation
Ayanian JZ, Cleary PD, Keogh JH, Noonan SJ, David-Kasdan JA, Epstein AM. Physicians’ beliefs about racial differences in referral for renal transplantation. American Journal Of Kidney Diseases 2004, 43: 350-357. PMID: 14750101, DOI: 10.1053/j.ajkd.2003.10.022.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsianAttitude of Health PersonnelBlack or African AmericanHealth Services AccessibilityHumansKidney Failure, ChronicKidney TransplantationMiddle AgedNephrologyPatient Acceptance of Health CarePhysician-Patient RelationsQuality of LifeReferral and ConsultationSurvival RateUnited StatesWhite PeopleConceptsRenal transplantationWhite patientsPatient-physician communicationBlack patientsQuality of lifeRacial differencesEnd-stage renal diseaseNephrologist's viewComorbid illnessesRenal diseaseTreatment optionsPatient preferencesPhysician biasPhysicians' beliefsPatientsPhysicians' viewsTransplantationPhysiciansCareSurvivalImportant reasonUS regionsNephrologistsDifferencesReferral
2003
Guideline Recommendations for Treatment of Schizophrenia: The Impact of Managed Care
Dickey B, Normand SL, Hermann RC, Eisen SV, Cortes DE, Cleary PD, Ware N. Guideline Recommendations for Treatment of Schizophrenia: The Impact of Managed Care. JAMA Psychiatry 2003, 60: 340-348. PMID: 12695310, DOI: 10.1001/archpsyc.60.4.340.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareAttitude to HealthFee-for-Service PlansFemaleFollow-Up StudiesGuideline AdherenceHealth Services ResearchHospitalizationHumansMaleManaged Care ProgramsMedicaidMedicareMiddle AgedOutcome Assessment, Health CarePersonal SatisfactionPractice Guidelines as TopicProspective StudiesQuality of LifeSchizophreniaConceptsTreatment of schizophreniaTreatment guidelinesMedicaid beneficiariesSchizophrenia Patient Outcomes Research Team (PORT) treatment recommendationsOutpatient mental health facilitiesDisabled Medicaid beneficiariesProspective observational studyHealth-related qualityHigh-risk adultsAdult Medicaid beneficiariesOutpatient medical recordsMain outcome measuresSchizophrenia treatment guidelinesClinician-reported outcomesWay mental health careMental health careSelf-reported qualityBehavioral health care organizationsMental health facilitiesDelivery of treatmentMental health benefitsClinical outcomesGuideline recommendationsOutpatient treatmentMedical records
2000
Health-related quality of life in patients with human immunodeficiency virus infection in the United States: results from the HIV cost and services utilization study
Hays R, Cunningham W, Sherbourne C, Wilson I, Wu A, Cleary P, McCaffrey D, Fleishman J, Crystal S, Collins R, Eggan F, Shapiro M, Bozzette S. Health-related quality of life in patients with human immunodeficiency virus infection in the United States: results from the HIV cost and services utilization study. The American Journal Of Medicine 2000, 108: 714-722. PMID: 10924648, DOI: 10.1016/s0002-9343(00)00387-9.Peer-Reviewed Original ResearchConceptsHealth-related qualityServices Utilization StudyHIV diseaseChronic diseasesPhysical functioningGeneral populationHIV CostUtilization studiesHuman immunodeficiency virus (HIV) diseaseHuman immunodeficiency virus (HIV) infectionSF-36 physical functioningMental health summary scoresMental healthAsymptomatic HIV diseaseImmunodeficiency virus infectionSymptomatic HIV diseaseWorse physical functioningHealth summary scoresUS general populationHealth insurance statusAttention of cliniciansCD4 countAdult patientsSubstantial morbidityImmunodeficiency syndrome
1997
Clinical Predictors of Declines in Physical Functioning in Persons With AIDS: Results of a Longitudinal Study
Wilson* I, Cleary† P. Clinical Predictors of Declines in Physical Functioning in Persons With AIDS: Results of a Longitudinal Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1997, 16: 343-349. PMID: 9420312, DOI: 10.1097/00042560-199712150-00006.Peer-Reviewed Original ResearchConceptsPhysical functioningIADL scoresWeight lossIndependent predictorsSymptom complexStaff-model health maintenance organizationBaseline IADL scoresInjection drug useLongitudinal cohort studySignificant independent predictorsPublic teaching hospitalAcademic group practiceHealth maintenance organizationCandida esophagitisChart reviewCohort studyNeurologic symptomsClinical factorsClinical predictorsAIDS clinicClinical correlatesTeaching hospitalGastrointestinal diseasesDaily livingBaseline functioning
1996
The influence of health-related quality of life and social characteristics on hospital use by patients with AIDS in the Boston Health Study.
Weissman J, Cleary P, Seage G, Gatsonis C, Haas J, Chasan-Taber S, Epstein A. The influence of health-related quality of life and social characteristics on hospital use by patients with AIDS in the Boston Health Study. Medical Care 1996, 34: 1037-56. PMID: 8843929, DOI: 10.1097/00005650-199610000-00005.Peer-Reviewed Original ResearchConceptsSystems of careHealth-related qualityHospital useMedical chartsDisease burdenNeuropsychological StatusBoston Health StudyTotal hospital daysOdds of admissionHealth-related factorsHospital daysIndependent predictorsImmunodeficiency syndromeStudy enrollmentPatient groupPatient interviewsProphylactic drugsSerious opportunistic diseaseOpportunistic diseasesHospital careDaily livingPatterns of useHealth StudyHospital billsClinical modelClinical predictors of functioning in persons with acquired immunodeficiency syndrome.
Wilson I, Cleary P. Clinical predictors of functioning in persons with acquired immunodeficiency syndrome. Medical Care 1996, 34: 610-23. PMID: 8656726, DOI: 10.1097/00005650-199606000-00010.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeActivities of Daily LivingAdolescentAdultBostonCross-Sectional StudiesDisabled PersonsFemaleGroup PracticeHealth Maintenance OrganizationsHealth Status IndicatorsHumansMaleMedical AuditMiddle AgedMultivariate AnalysisOutpatient Clinics, HospitalPredictive Value of TestsQuality of LifeRegression AnalysisReproducibility of ResultsSurveys and QuestionnairesConceptsEnergy/fatiguePoor mental healthPhysical functioningNeurologic symptomsFever symptomsMental healthZidovudine useWeight lossImmunodeficiency syndromeSignificant predictorsStaff-model health maintenance organizationLower white blood cell countHuman immunodeficiency virus clinicChronic obstructive pulmonary diseaseWhite blood cell countHistory of asthmaLower hemoglobin levelsObstructive pulmonary diseaseBlood cell countMultivariable regression modelsHealth maintenance organizationHospital-based group practiceCross-sectional analysisSpecific clinical interventionsChart review
1995
Variation in the Use of Cardiac Procedures after Acute Myocardial Infarction
Guadagnoli E, Hauptman P, Ayanian J, Pashos C, McNeil B, Cleary P. Variation in the Use of Cardiac Procedures after Acute Myocardial Infarction. New England Journal Of Medicine 1995, 333: 573-578. PMID: 7623908, DOI: 10.1056/nejm199508313330908.Peer-Reviewed Original ResearchConceptsHealth-related qualityPatterns of treatmentAcute myocardial infarctionCardiac proceduresRate of useCoronary angiographyMyocardial infarctionMore metabolic equivalentsLikelihood of deathYears of ageLarge geographic differencesMetabolic equivalentsClinical subgroupsMortality ratePatientsCase mixGreater riskInfarctionAngiographyEnergy expenditureTwo-year periodFrequency of useHigh rateTreatmentPhysiciansHealth-related quality of life in patients with advanced prostate cancer: A multinational perspective
Cleary P, Morrissey G, Oster G. Health-related quality of life in patients with advanced prostate cancer: A multinational perspective. Quality Of Life Research 1995, 4: 207-220. PMID: 7613531, DOI: 10.1007/bf02260860.Peer-Reviewed Original ResearchConceptsHealth-related qualityAdvanced prostate cancerProstate cancerSelf-administered patient questionnaireUntreated metastatic prostate cancerObjective tumor responseDomains of HRQOLMetastatic prostate cancerAntiandrogen therapyPatient questionnaireStudy entryTreatment failureStudy treatmentTumor responseClinical trialsPatientsCancerTrialsTreatmentQuestionnaireHRQoLAntiandrogensTherapyCastrationFocus of concernThe influence of socioeconomic status on change in health status after hospitalization
Guadagnoli E, Cleary P, Mcneil B. The influence of socioeconomic status on change in health status after hospitalization. Social Science & Medicine 1995, 40: 1399-1406. PMID: 7638648, DOI: 10.1016/0277-9536(94)00266-v.Peer-Reviewed Original ResearchConceptsHigh-SES patientsHigh-income patientsHealth statusChest painSurgical patientsHospital recordsSocioeconomic statusDaily livingUniversity-affiliated teaching hospitalLow-SES patientsHealth status scoresPatients' hospital recordsWorse health statusHospital dischargeHospital admissionStatus scoreTeaching hospitalInstrumental activitiesPatientsBasic activitiesHospitalizationPainAmount of declineAdmissionVariety of outcomesLinking clinical variables with health-related quality of life. A conceptual model of patient outcomes.
Wilson I, Cleary P. Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. JAMA 1995, 273: 59-65. PMID: 7996652, DOI: 10.1001/jama.273.1.59.Peer-Reviewed Original ResearchConceptsClinical variablesMeasures of HRQLHealth-related qualityGeneral health perceptionTraditional clinical variablesHealth care systemPatient outcomesHealth perceptionOutcome measuresHealth outcomesCare systemOutcomesPhysiological factorsSpecific causal relationshipsOverall qualityHRQLCausal relationship
1994
The effects of rG-CSF on health-related quality of life in children with congenital agranulocytosis
Cleary P, Morrissey G, Yver A, Oster G. The effects of rG-CSF on health-related quality of life in children with congenital agranulocytosis. Quality Of Life Research 1994, 3: 307-315. PMID: 7841964, DOI: 10.1007/bf00451722.Peer-Reviewed Original ResearchConceptsHealth-related qualityGeneral health perceptionStudy patientsCongenital agranulocytosisHealth perceptionMulticentre phase II clinical trialPhase II clinical trialRecombinant human granulocyte colony-stimulating factorRG-CSF therapyAspects of HRQOLInitiation of treatmentGranulocyte colony-stimulating factorHuman granulocyte colony-stimulating factorValue of treatmentColony-stimulating factorPatient populationFunctional statusOne-half monthsSuch therapyClinical trialsActivity limitationsTherapyStudy centersHRQoLAgranulocytosisUsing health-related quality-of-life information
Tsevat J, Weeks J, Guadagnoli E, Tosteson A, Mangione C, Pliskin J, Weinstein M, Cleary P. Using health-related quality-of-life information. Journal Of General Internal Medicine 1994, 9: 576-582. PMID: 7823230, DOI: 10.1007/bf02599287.Peer-Reviewed Original Research
1993
Health-Related Quality of Life in Persons with Acquired Immune Deficiency Syndrome
Cleary P, Fowler F, Weissman J, Massagli M, Wilson I, Seage G, Gatsonis C, Epstein A. Health-Related Quality of Life in Persons with Acquired Immune Deficiency Syndrome. Medical Care 1993, 31: 569-580. PMID: 8326772, DOI: 10.1097/00005650-199307000-00001.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHealth-related qualityQuality of lifeHealth statusAcquired Immune Deficiency SyndromeGlobal health assessmentImmune deficiency syndromeFunctioning of personsHIV infectionImmunodeficiency virusFunctional statusPrimary careDeficiency syndromeFunctional impairmentBest predictorDiscrete symptomsSymptomsMental healthImportant signHealth assessmentAverage severityStrongest correlateFace interviewsValid measureStatusThe Importance of Co-existent Disease in the Occurrence of Postoperative Complications and One-Year Recovery in Patients Undergoing Total Hip Replacement
Greenfield S, Apolone G, McNeil B, Cleary P. The Importance of Co-existent Disease in the Occurrence of Postoperative Complications and One-Year Recovery in Patients Undergoing Total Hip Replacement. Medical Care 1993, 31: 141-154. PMID: 8433577, DOI: 10.1097/00005650-199302000-00005.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAgedCohort StudiesComorbidityDemographyFemaleHealth StatusHip ProsthesisHumansLogistic ModelsMaleMiddle AgedOdds RatioOutcome Assessment, Health CarePostoperative ComplicationsPrognosisQuality of LifeSeverity of Illness IndexSurveys and QuestionnairesUnited StatesConceptsCo-existent diseaseTotal hip replacementPostoperative complicationsHip replacementFunctional outcomeMedical recordsTotal hip replacement patientsFunctional outcome 1 yearHealth-related qualityTime of surgeryPost-operative complicationsSeverity of illnessOutcomes 1 yearHip replacement patientsPatients' medical recordsSignificant predictorsEffectiveness of careOne-year recoveryMedical record informationHospital complicationsICED scoreComorbid diseasesComplication rateHospital dischargePatient characteristicsUsing patient reports to assess health-related quality of life after total hip replacement
Cleary P, Reilly D, Greenfield S, Mulley A, Wexler L, Frankel F, McNeil B. Using patient reports to assess health-related quality of life after total hip replacement. Quality Of Life Research 1993, 2: 3-11. PMID: 8490615, DOI: 10.1007/bf00642884.Peer-Reviewed Original ResearchConceptsTotal hip replacementHip replacementUnilateral total hip replacementHealth-related qualityOutcomes 1 yearQuestionnaire 12 monthsProcess of careGood construct validityReponse rateRheumatoid arthritisFunctional statusMedical recordsTeaching hospitalPatient reportsHip arthroplastyHealth statusDisease severitySociodemographic characteristicsPatientsStrongest predictorConstruct validityQuestionnaireStatusHospitalizationArthritis