1995
Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes.
Wilson I, Cleary P. Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. JAMA 1995, 273: 59-65. PMID: 7996652, DOI: 10.1001/jama.273.1.59.Peer-Reviewed Original ResearchConceptsClinical variablesMeasures of HRQLHealth-related qualityGeneral health perceptionTraditional clinical variablesHealth care systemPatient outcomesHealth perceptionOutcome measuresHealth outcomesCare systemOutcomesPhysiological factorsSpecific causal relationshipsOverall qualityHRQLCausal relationship
1994
The effects of rG-CSF on health-related quality of life in children with congenital agranulocytosis
Cleary P, Morrissey G, Yver A, Oster G. The effects of rG-CSF on health-related quality of life in children with congenital agranulocytosis. Quality Of Life Research 1994, 3: 307-315. PMID: 7841964, DOI: 10.1007/bf00451722.Peer-Reviewed Original ResearchConceptsHealth-related qualityGeneral health perceptionStudy patientsCongenital agranulocytosisHealth perceptionMulticentre phase II clinical trialPhase II clinical trialRecombinant human granulocyte colony-stimulating factorRG-CSF therapyAspects of HRQOLInitiation of treatmentGranulocyte colony-stimulating factorHuman granulocyte colony-stimulating factorValue of treatmentColony-stimulating factorPatient populationFunctional statusOne-half monthsSuch therapyClinical trialsActivity limitationsTherapyStudy centersHRQoLAgranulocytosis