2017
High dose-rate Intra-Operative Radiation Therapy During High Risk Genitourinary Surgery: Initial Observations and a Proposal for its Study in Bladder Cancer
Kates M, Chappidi MR, Brant A, Milbar N, Sopko NA, Meyer C, Terezakis SA, Herman JM, Efron JE, Safar B, Tran PT, Ahuja N, Pierorazio PM, Bivalacqua TJ. High dose-rate Intra-Operative Radiation Therapy During High Risk Genitourinary Surgery: Initial Observations and a Proposal for its Study in Bladder Cancer. Bladder Cancer 2017, 3: 191-199. PMID: 28824947, PMCID: PMC5545919, DOI: 10.3233/blc-170104.Peer-Reviewed Original ResearchSurgical margin statusBladder cancerGenitourinary surgeryMargin statusInstitutional experienceIntra-operative radiation therapyRadiation therapyHigh-risk bladder cancerPositive surgical margin statusMulti-institutional registryRecurrence-free survivalEffective local controlGI complicationsSarcomatoid histologyAdvanced diseaseFree survivalComplication rateOverall survivalPrimary outcomeRetrospective reviewSuch patientsRecurrent tumorsUrothelial cancerWound infectionUrothelial histology
2015
Standard Fractionation External Beam Radiation Therapy With and Without Intraoperative Radiation Therapy for Patients With Locally Recurrent Rectal Cancer
Kishan A, Moningi S, Kumar R, Ancukiewicz M, Ahuja N, Gearhart S, Efron J, Herman J, Hong T. Standard Fractionation External Beam Radiation Therapy With and Without Intraoperative Radiation Therapy for Patients With Locally Recurrent Rectal Cancer. International Journal Of Radiation Oncology • Biology • Physics 2015, 93: e145. DOI: 10.1016/j.ijrobp.2015.07.918.Peer-Reviewed Original Research
2014
The Impact of Postoperative Complications on the Administration of Adjuvant Therapy Following Pancreaticoduodenectomy for Adenocarcinoma
Wu W, He J, Cameron JL, Makary M, Soares K, Ahuja N, Rezaee N, Herman J, Zheng L, Laheru D, Choti MA, Hruban RH, Pawlik TM, Wolfgang CL, Weiss MJ. The Impact of Postoperative Complications on the Administration of Adjuvant Therapy Following Pancreaticoduodenectomy for Adenocarcinoma. Annals Of Surgical Oncology 2014, 21: 2873-2881. PMID: 24770680, PMCID: PMC4454347, DOI: 10.1245/s10434-014-3722-6.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasm StagingPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsPrognosisRadiotherapy, AdjuvantRetrospective StudiesSurvival RateConceptsAdjuvant therapyPostoperative complicationsMedian survivalMultivariate analysisClavien-Dindo complication gradeTherapy warrants further investigationMultimodality adjuvant therapyOverall complication rateMethodsA retrospective reviewGrade of complicationsLonger median survivalLength of stayWarrants further investigationAdjuvant chemotherapyMedian TTANeoadjuvant approachComplication gradeComplication rateSevere complicationsRetrospective reviewClinicopathological dataResultsA totalPancreaticoduodenectomyRadiation therapyComplicationsHigh-dose-rate intraoperative radiation therapy: the nuts and bolts of starting a program
Moningi S, Armour EP, Terezakis SA, Efron JE, Gearhart SL, Bivalacqua TJ, Kumar R, Le Y, Ng S, Wolfgang CL, Zellars RC, Ellsworth SG, Ahuja N, Herman JM. High-dose-rate intraoperative radiation therapy: the nuts and bolts of starting a program. Journal Of Contemporary Brachytherapy 2014, 6: 99-105. PMID: 24790628, PMCID: PMC4003434, DOI: 10.5114/jcb.2014.42027.Peer-Reviewed Original ResearchRate intraoperative radiation therapyIntraoperative radiation therapyRadiation therapyLocal controlGroup of patientsEffective local controlPelvic solid tumorsHDR-IORTRecurrent tumorsTrue efficacySolid tumorsMultidisciplinary approachPatientsTherapyTumorsIORT programProper administrationIORTSpecialized institutionsMalignancyOncologistsAnesthesiologistsPhysics staffNursesSurgeons
2007
The role of radiation in retroperitoneal sarcomas: a surgical perspective
Pawlik TM, Ahuja N, Herman JM. The role of radiation in retroperitoneal sarcomas: a surgical perspective. Current Opinion In Oncology 2007, 19: 359-366. PMID: 17545800, DOI: 10.1097/cco.0b013e328122d757.Peer-Reviewed Original ResearchConceptsExternal beam radiation therapyBeam radiation therapyIntraoperative radiation therapyLocal recurrence rateRadiation therapyRetroperitoneal sarcomaRecurrence rateAdjuvant external beam radiation therapyLocal recurrence-free survivalPreoperative external beam radiation therapyRadiation-related morbidityRetroperitoneal sarcoma patientsLocal control rateLocal-regional controlPreoperative radiation therapyRecurrence-free survivalTiming of administrationSurgical patientsTumor resectabilitySarcoma patientsTechniques of deliveryControl rateSurgical perspectiveAdditional toxicityRecent studies