2013
The CpG Island Methylator Phenotype: What's in a Name?
Hughes LA, Melotte V, de Schrijver J, de Maat M, Smit VT, Bovée JV, French PJ, van den Brandt PA, Schouten LJ, de Meyer T, van Criekinge W, Ahuja N, Herman JG, Weijenberg MP, van Engeland M. The CpG Island Methylator Phenotype: What's in a Name? Cancer Research 2013, 73: 5858-5868. PMID: 23801749, DOI: 10.1158/0008-5472.can-12-4306.Peer-Reviewed Original ResearchConceptsCpG island methylator phenotypeTranslocation methylcytosine dioxygenase 2Tumor typesMethylator phenotypePrimary human astrocytesHuman neoplasiaIsocitrate dehydrogenase 1 (IDH1) mutationCpG island promoter methylationColorectal cancerOllier's diseaseAdrenocortical carcinomaProstate cancerMultiple enchondromasHuman astrocytesClinical practiceRenal cellsIDH2 mutationsCancer typesCancerDioxygenase 2Promoter methylationFunction mutationsMafucci's syndromeNeoplasiaLeukemia
2010
M1629 Preoperative Biopsy Findings Correlate Poorly With Postoperative Findings in IBD-Associated Neoplasia
Gearhart S, Wick E, Ahuja N, Montgomery E, Efron J. M1629 Preoperative Biopsy Findings Correlate Poorly With Postoperative Findings in IBD-Associated Neoplasia. Gastroenterology 2010, 138: s-870. DOI: 10.1016/s0016-5085(10)64018-8.Peer-Reviewed Original Research
2008
Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Associated Neoplasia
Dhir M, Montgomery EA, Glöckner SC, Schuebel KE, Hooker CM, Herman JG, Baylin SB, Gearhart SL, Ahuja N. Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Associated Neoplasia. Journal Of Gastrointestinal Surgery 2008, 12: 1745-1753. PMID: 18716850, PMCID: PMC3976145, DOI: 10.1007/s11605-008-0633-5.Peer-Reviewed Original ResearchConceptsInflammatory Bowel Disease-Associated NeoplasiaIBD colitisNormal colon samplesColorectal cancerLogistic regression modelsAssociated neoplasiaWnt Signaling Pathway GenesMultivariate logistic regression modelPathogenesis of IBDUnivariate logistic regression modelDevelopment of IBDSporadic colorectal cancerProgressive increaseEarly eventsIBD samplesRegression modelsPathway genesCRC samplesColitisNeoplasiaIBDPathway dysregulationColon samplesSignaling Pathway GenesTissue samples557 Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Neoplasia
Dhir M, Montgomery E, Schuebel K, Gearhart S, Ahuja N. 557 Epigenetic Regulation of WNT Signaling Pathway Genes in Inflammatory Bowel Disease (IBD) Neoplasia. Gastroenterology 2008, 134: a-848-a-849. DOI: 10.1016/s0016-5085(08)63975-x.Peer-Reviewed Original Research