Ningning Zhang
Associate Research Scientist in GeneticsAbout
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Titles
Associate Research Scientist in Genetics
Education & Training
- Associate Research Scientist
- Yale (2026)
- Postdoctoral Associate
- Yale (2025)
- PhD
- Institute of Microbiology, Chinese Academy of Sciences, State Key Laboratory of Microbial Resources (2020)
Research
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Ningning Zhang's published research.
Jun Lu, PhD
Dianqing (Dan) Wu, PhD
Hongyue Zhou
Wenwen Tang, PhD
Andres Hidalgo, PhD
Barani Kumar Rajendran, BS
Publications
2025
Archaeal replicative primase mediates DNA double-strand break repair.
Xiong D, Li Z, Qi W, Wang S, Huang J, Zhang N, Zhang Z, Huang L. Archaeal replicative primase mediates DNA double-strand break repair. Nucleic Acids Res 2025, 53 PMID: 40272359, DOI: 10.1093/nar/gkaf322.Peer-Reviewed Original ResearchThe interplay between Salmonella and host: Mechanisms and strategies for bacterial survival.
Zhao H, Zhang X, Zhang N, Zhu L, Lian H. The interplay between Salmonella and host: Mechanisms and strategies for bacterial survival. Cell Insight 2025, 4: 100237. PMID: 40177681, DOI: 10.1016/j.cellin.2025.100237.Peer-Reviewed Original Research
2024
Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues
Bai Z, Zhang D, Gao Y, Tao B, Zhang D, Bao S, Enninful A, Wang Y, Li H, Su G, Tian X, Zhang N, Xiao Y, Liu Y, Gerstein M, Li M, Xing Y, Lu J, Xu M, Fan R. Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues. Cell 2024, 187: 6760-6779.e24. PMID: 39353436, PMCID: PMC11568911, DOI: 10.1016/j.cell.2024.09.001.Peer-Reviewed Original ResearchCitationsAltmetricConceptsRNA biologyWhole-transcriptome sequencingMicroRNA regulatory networkSplicing dynamicsDeterministic barcodingRNA speciesRNA processingRNA variantsFFPE tissuesRegulatory networksTranscriptome sequencingSpliced isoformsNon-malignant cellsTumor clonal architecturesClonal architectureGene expressionCellular dynamicsRNAArchival formalin-fixed paraffin-embedded tissueMalignant subclonesFormalin-fixed paraffin-embedded (FFPEFFPE samplesParaffin-embedded (FFPEBiologyHuman lymphomasProtocol for detecting glycoRNAs using metabolic labeling and northwestern blot
Li L, Zhang N, Pantoja C, Wang Y, Lu J. Protocol for detecting glycoRNAs using metabolic labeling and northwestern blot. STAR Protocols 2024, 5: 103321. PMID: 39298321, PMCID: PMC11426122, DOI: 10.1016/j.xpro.2024.103321.Peer-Reviewed Original ResearchCitationsWnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis
Luan Y, Hu J, Wang Q, Wang X, Li W, Qu R, Yang C, Rajendran B, Zhou H, Liu P, Zhang N, Shi Y, Liu Y, Tang W, Lu J, Wu D. Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis. Cell Reports 2024, 43: 113934. PMID: 38461416, PMCID: PMC11064424, DOI: 10.1016/j.celrep.2024.113934.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCD8+ T cell activationNeutrophil productionNeutrophil plasticitySplenic extramedullary myelopoiesisFamily member 5T cell activationInnate immune cellsSplenic stromal cellsDSS-Induced ColitisAnti-inflammatory protectionCD101 expressionPro-inflammatory activitySplenic myelopoiesisExtramedullary myelopoiesisBone marrowImmune cellsSplenic neutrophilsMember 5Autoimmune diseasesInflammatory outcomesCell activationStromal cellsColitisSplenic productionElevated numbersCell surface RNAs control neutrophil recruitment
Zhang N, Tang W, Torres L, Wang X, Ajaj Y, Zhu L, Luan Y, Zhou H, Wang Y, Zhang D, Kurbatov V, Khan S, Kumar P, Hidalgo A, Wu D, Lu J. Cell surface RNAs control neutrophil recruitment. Cell 2024, 187: 846-860.e17. PMID: 38262409, PMCID: PMC10922858, DOI: 10.1016/j.cell.2023.12.033.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCell surfaceMammalian homologOuter cell surfaceRNA transportGlycan modificationsMammalian cellsSID-1Cellular functionsRecruitment to inflammatory sitesGlycoRNARNAMurine neutrophilsFunctional significanceNeutrophil recruitmentNeutrophil recruitment to inflammatory sitesBiological importanceCellsNeutrophil adhesionReduced neutrophil adhesionHomologyGlycansGenesInflammatory sitesRecruitmentEndothelial cells
2020
The Sac10b homolog from Sulfolobus islandicus is an RNA chaperone.
Zhang N, Guo L, Huang L. The Sac10b homolog from Sulfolobus islandicus is an RNA chaperone. Nucleic Acids Res 2020, 48: 9273-9284. PMID: 32761152, DOI: 10.1093/nar/gkaa656.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
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Honors
honor Tom and Joan Steitz RNA Fellows
02/01/2024Yale University AwardYaleDetailsUnited Stateshonor ASH Abstract Achievement Awards
12/06/2023International AwardAmerican Society of HematologyDetailsUnited States
News
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News
- February 28, 2024
YCC Research Publications
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Contacts
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Mailing Address
Genetics
10 Amistad Street, 214K
New Haven, CT 06519
United States