Tubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function
Avigan ZM, Singh N, Kliegel JA, Weiss M, Moeckel GW, Cantley LG. Tubular Cell Dropout in Preimplantation Deceased Donor Biopsies as a Predictor of Delayed Graft Function. Transplantation Direct 2021, 7: e716. PMID: 34476295, PMCID: PMC8384397, DOI: 10.1097/txd.0000000000001168.Peer-Reviewed Original ResearchDeceased donor kidney transplantDonor biopsiesGraft functionTubular injuryTubular cellsDelayed graft functionAcute tubular injuryDonor kidney transplantsConventional histopathologic evaluationPotential therapeutic interventionsMass cytometry analysisTubular cell lossDGF riskGraft outcomeTransplant recipientsKidney transplantPharmacologic therapyDeceased donorsMacrophage infiltrationHistopathologic evaluationLiving donorsDonor factorsCold ischemiaHistopathologic analysisCell dropout