2024
A neural network model of differentiation and integration of competing memories
Ritvo V, Nguyen A, Turk-Browne N, Norman K. A neural network model of differentiation and integration of competing memories. ELife 2024, 12: rp88608. PMID: 39319791, PMCID: PMC11424095, DOI: 10.7554/elife.88608.Peer-Reviewed Original ResearchConceptsNeural network modelUnsupervised neural network modelUnsupervised learning mechanismLearning mechanismLearning modelsNetwork modelComputational explanationInactive memoryNeural representationActive competitorsDiverse setRepresentationMemoryRepresentation of memoryMemory literatureBrain regionsNovel predictionsInfant neuroscience: how to measure brain activity in the youngest minds
Turk-Browne N, Aslin R. Infant neuroscience: how to measure brain activity in the youngest minds. Trends In Neurosciences 2024, 47: 338-354. PMID: 38570212, DOI: 10.1016/j.tins.2024.02.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFunctional magnetic resonance imagingFunctional near-infrared spectroscopyMeasure brain activityBrain activityApplication of functional magnetic resonance imagingHuman infantsCognitive neuroscienceCognitive tasksInfant brainAwake infantsMagnetic resonance imagingNear-infrared spectroscopyMagnetoencephalographyMindfulnessResonance imagingNon-invasive methodInfantsElectroencephalography
2023
Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements
Sherman B, Harris B, Turk-Browne N, Sinha R, Goldfarb E. Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements. Journal Of Neuroscience 2023, 43: 7198-7212. PMID: 37813570, PMCID: PMC10601369, DOI: 10.1523/jneurosci.0916-23.2023.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMemory enhancementEpisodic memoryAssociative memoryEpisodic memory encodingBrain regionsHigh-resolution functional magnetic resonance imagingHuman hippocampusHigh-resolution fMRIStress-related hormone cortisolHormone cortisolMemory benefitsEmotional memoryMemory encodingEmotional eventsEmotional associationsHippocampal representationsHippocampal signaturesFunctional neuroimagingHippocampal mechanismsStressful eventsFunctional connectivityHippocampal functionMemory formationSalient informationFunctional networks in the infant brain during sleep and wake states
Yates T, Ellis C, Turk-Browne N. Functional networks in the infant brain during sleep and wake states. Cerebral Cortex 2023, 33: 10820-10835. PMID: 37718160, DOI: 10.1093/cercor/bhad327.Peer-Reviewed Original ResearchConceptsFunctional connectivityMagnetic resonance imaging (MRI) scansFunctional magnetic resonance imaging (fMRI) scansWhole-brain functional connectivityResonance imaging scansInfant stateFunctional networksImaging scansAdult stateNatural sleepFunctional brain networksInfantsAwake restAwake fMRIInfant brainSleepBrain networksAdultsFrontoparietal control networkWake statesState of consciousnessDevelopmental changesBrainIntracranial Entrainment Reveals Statistical Learning across Levels of Abstraction
Sherman B, Aljishi A, Graves K, Quraishi I, Sivaraju A, Damisah E, Turk-Browne N. Intracranial Entrainment Reveals Statistical Learning across Levels of Abstraction. Journal Of Cognitive Neuroscience 2023, 35: 1312-1328. PMID: 37262357, DOI: 10.1162/jocn_a_02012.Peer-Reviewed Original ResearchPerception and memory retrieval states are reflected in distributed patterns of background functional connectivity
Li Y, Wang Y, Turk-Browne N, Kuhl B, Hutchinson J. Perception and memory retrieval states are reflected in distributed patterns of background functional connectivity. NeuroImage 2023, 276: 120221. PMID: 37290674, PMCID: PMC10484747, DOI: 10.1016/j.neuroimage.2023.120221.Peer-Reviewed Original ResearchConceptsDefault mode networkMemory retrievalCognitive stateRetrieval statesRetrosplenial cortexFunctional connectivityDistinct neural statesTarget of perceptionLarge-scale brain networksControl networkHuman neuroimaging studiesSame visual inputPerception statesCognitive processingBackground connectivityHuman fMRIVisual stimuliNeuroimaging studiesBrain networksMode networkNeural statesVisual inputNeural activityPatterns of connectivityPerception
2022
Face processing in the infant brain after pandemic lockdown
Yates T, Ellis C, Turk‐Browne N. Face processing in the infant brain after pandemic lockdown. Developmental Psychobiology 2022, 65: e22346. PMID: 36567649, PMCID: PMC9877889, DOI: 10.1002/dev.22346.Peer-Reviewed Original ResearchConceptsFusiform face areaVisual experienceInfant brainDifferent face identitiesGreater neural activityPost-lockdown groupFace processingRepetition enhancementFace identityRepetition suppressionSuppression taskFace areaNeural activitySame identityDifferent identitiesSerendipitous studyFFA responseFacePandemic lockdownCOVID-19 pandemicFMRIQuantity/qualityInfantsExperienceIdentityNeural event segmentation of continuous experience in human infants
Yates T, Skalaban L, Ellis C, Bracher A, Baldassano C, Turk-Browne N. Neural event segmentation of continuous experience in human infants. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2200257119. PMID: 36252007, PMCID: PMC9618143, DOI: 10.1073/pnas.2200257119.Peer-Reviewed Original ResearchConceptsEarly visual regionsEvent segmentationVisual regionsAdults' brain activityContinuous sensory inputFunctional MRI dataEvent cognitionNaturalistic perceptionBehavioral judgmentsInfants' segmentationEvent boundariesNeural patternsBrain activitySensory regionsContinuous experienceSimplified taskInfant brainHuman infantsAssociative regionsSensory inputTemporal integrationAwake infantsBrain regionsAdult experienceTemporal precisionBrain charts for the human lifespan
Bethlehem RAI, Seidlitz J, White SR, Vogel JW, Anderson KM, Adamson C, Adler S, Alexopoulos GS, Anagnostou E, Areces-Gonzalez A, Astle DE, Auyeung B, Ayub M, Bae J, Ball G, Baron-Cohen S, Beare R, Bedford SA, Benegal V, Beyer F, Blangero J, Blesa Cábez M, Boardman JP, Borzage M, Bosch-Bayard JF, Bourke N, Calhoun VD, Chakravarty MM, Chen C, Chertavian C, Chetelat G, Chong YS, Cole JH, Corvin A, Costantino M, Courchesne E, Crivello F, Cropley VL, Crosbie J, Crossley N, Delarue M, Delorme R, Desrivieres S, Devenyi GA, Di Biase MA, Dolan R, Donald KA, Donohoe G, Dunlop K, Edwards AD, Elison JT, Ellis CT, Elman JA, Eyler L, Fair DA, Feczko E, Fletcher PC, Fonagy P, Franz CE, Galan-Garcia L, Gholipour A, Giedd J, Gilmore JH, Glahn DC, Goodyer IM, Grant PE, Groenewold NA, Gunning FM, Gur RE, Gur RC, Hammill CF, Hansson O, Hedden T, Heinz A, Henson RN, Heuer K, Hoare J, Holla B, Holmes AJ, Holt R, Huang H, Im K, Ipser J, Jack CR, Jackowski AP, Jia T, Johnson KA, Jones PB, Jones DT, Kahn RS, Karlsson H, Karlsson L, Kawashima R, Kelley EA, Kern S, Kim KW, Kitzbichler MG, Kremen WS, Lalonde F, Landeau B, Lee S, Lerch J, Lewis JD, Li J, Liao W, Liston C, Lombardo MV, Lv J, Lynch C, Mallard TT, Marcelis M, Markello RD, Mathias SR, Mazoyer B, McGuire P, Meaney MJ, Mechelli A, Medic N, Misic B, Morgan SE, Mothersill D, Nigg J, Ong MQW, Ortinau C, Ossenkoppele R, Ouyang M, Palaniyappan L, Paly L, Pan PM, Pantelis C, Park MM, Paus T, Pausova Z, Paz-Linares D, Pichet Binette A, Pierce K, Qian X, Qiu J, Qiu A, Raznahan A, Rittman T, Rodrigue A, Rollins CK, Romero-Garcia R, Ronan L, Rosenberg MD, Rowitch DH, Salum GA, Satterthwaite TD, Schaare HL, Schachar RJ, Schultz AP, Schumann G, Schöll M, Sharp D, Shinohara RT, Skoog I, Smyser CD, Sperling RA, Stein DJ, Stolicyn A, Suckling J, Sullivan G, Taki Y, Thyreau B, Toro R, Traut N, Tsvetanov KA, Turk-Browne NB, Tuulari JJ, Tzourio C, Vachon-Presseau É, Valdes-Sosa MJ, Valdes-Sosa PA, Valk SL, van Amelsvoort T, Vandekar SN, Vasung L, Victoria LW, Villeneuve S, Villringer A, Vértes PE, Wagstyl K, Wang YS, Warfield SK, Warrier V, Westman E, Westwater ML, Whalley HC, Witte AV, Yang N, Yeo B, Yun H, Zalesky A, Zar HJ, Zettergren A, Zhou JH, Ziauddeen H, Zugman A, Zuo XN, Bullmore E, Alexander-Bloch A. Brain charts for the human lifespan. Nature 2022, 604: 525-533. PMID: 35388223, PMCID: PMC9021021, DOI: 10.1038/s41586-022-04554-y.Peer-Reviewed Original ResearchIncreasing stimulus similarity drives nonmonotonic representational change in hippocampus
Wammes J, Norman KA, Turk-Browne N. Increasing stimulus similarity drives nonmonotonic representational change in hippocampus. ELife 2022, 11: e68344. PMID: 34989336, PMCID: PMC8735866, DOI: 10.7554/elife.68344.Peer-Reviewed Original ResearchConceptsRepresentational changeHigh-level visual regionsShaped functionPairs of stimuliHigh-resolution fMRIStimulus similarityVisual regionsHuman participantsHippocampal learningMemoryPlasticity hypothesisCoactivationFMRIHippocampusGyrusStimuliWide enough rangeContradictory resultsParticipantsImage similarityLearningHypothesisU-shapeSimilar imagesEnough range
2021
Retinotopic organization of visual cortex in human infants
Ellis CT, Yates TS, Skalaban LJ, Bejjanki VR, Arcaro MJ, Turk-Browne NB. Retinotopic organization of visual cortex in human infants. Neuron 2021, 109: 2616-2626.e6. PMID: 34228960, DOI: 10.1016/j.neuron.2021.06.004.Peer-Reviewed Original ResearchConceptsVisual cortexFunctional magnetic resonance imagingAdult visual cortexMagnetic resonance imagingVisual areas V1Retinotopic organizationRetinotopic mapResonance imagingHorizontal meridianRetinotopic mappingCortexSubsequent developmental changesArea V1InfantsHuman infantsFunctional maturityFunctional mapsDevelopmental changesLow spatial frequenciesEarly maturationExtrastriateMonthsLearning hierarchical sequence representations across human cortex and hippocampus
Henin S, Turk-Browne NB, Friedman D, Liu A, Dugan P, Flinker A, Doyle W, Devinsky O, Melloni L. Learning hierarchical sequence representations across human cortex and hippocampus. Science Advances 2021, 7: eabc4530. PMID: 33608265, PMCID: PMC7895424, DOI: 10.1126/sciadv.abc4530.Peer-Reviewed Original ResearchConceptsOrdinal positionTransitional probabilitiesBrain areasEarliest brain areasGradient of complexityVisual sequencesCortico-hippocampal circuitsNeural representationNeural trackingEarly processingBrain's abilityTemporal regularityStatistical learningAssociative regionsSensory inputLow-level featuresHuman cortexSequence representationParallel computational systemsMultiple levelsComputational systemsIntracranial electrodesCortexHippocampusProcessing
2020
Searching through functional space reveals distributed visual, auditory, and semantic coding in the human brain
Kumar S, Ellis CT, O’Connell T, Chun MM, Turk-Browne NB. Searching through functional space reveals distributed visual, auditory, and semantic coding in the human brain. PLOS Computational Biology 2020, 16: e1008457. PMID: 33270655, PMCID: PMC7738169, DOI: 10.1371/journal.pcbi.1008457.Peer-Reviewed Original ResearchConceptsBrain functionHuman brainHuman brain functionLanguage processing modelsNatural language processing modelsSearchlight analysisSearchlight approachSemantic codingObject representationsAuditory featuresBrain activityStrict modularityDecoding accuracyProcessing modelFMRI techniquesFMRI methodsAtlas parcellationCluster correctionComputational modelSemantic featuresDeep neural networksFoundational questionsAnatomical biasLocalized representationSearchlightEmergence and organization of adult brain function throughout child development
Yates TS, Ellis CT, Turk-Browne NB. Emergence and organization of adult brain function throughout child development. NeuroImage 2020, 226: 117606. PMID: 33271266, PMCID: PMC8323508, DOI: 10.1016/j.neuroimage.2020.117606.Peer-Reviewed Original ResearchConceptsFMRI activityDevelopmental trajectoriesAdult cognitive neuroscienceInferior frontal gyrusLateral occipital cortexPain-related eventsCognitive neuroscienceFrontal gyrusFunctional neuroanatomyDevelopmental differencesChild developmentAge-related changesCognitive functionDifferent brain regionsSame movieHuman brain developmentNaturalistic approachOccipital cortexBrain regionsAdult brain functionBrain functionChronological ageYoung childrenBrain developmentBrain spaceRe-imagining fMRI for awake behaving infants
Ellis CT, Skalaban LJ, Yates TS, Bejjanki VR, Córdova NI, Turk-Browne NB. Re-imagining fMRI for awake behaving infants. Nature Communications 2020, 11: 4523. PMID: 32908125, PMCID: PMC7481790, DOI: 10.1038/s41467-020-18286-y.Peer-Reviewed Original ResearchConceptsCognitive tasksFunctional magnetic resonance imaging studyTask-evoked activityMagnetic resonance imaging studyCognitive neuroscienceResonance imaging studyFMRI acquisitionHuman infantsFMRI datasetsHuman brainFMRITaskUnique methodological challengesMethodological challengesImaging studiesNeuroscienceInner workingsInfantsMindImportant insightsAcquisitionBrainDecisionsStatistical prediction of the future impairs episodic encoding of the present
Sherman BE, Turk-Browne NB. Statistical prediction of the future impairs episodic encoding of the present. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 22760-22770. PMID: 32859755, PMCID: PMC7502714, DOI: 10.1073/pnas.2013291117.Peer-Reviewed Original ResearchConceptsFunction of memoryEpisodic encodingSource recallEpisodic memoryUpcoming itemsStatistical learningAdaptive purposeFuture experiencesMemoryCurrent itemPast experienceBrain imagingSpecific experiencesBehavioral testsIdiosyncratic propertiesItemsFuture situationsExperienceParticular momentHippocampusRecallEncodingSimilar situationLearningSituation
2018
Learning Naturalistic Temporal Structure in the Posterior Medial Network
Aly M, Chen J, Turk-Browne NB, Hasson U. Learning Naturalistic Temporal Structure in the Posterior Medial Network. Journal Of Cognitive Neuroscience 2018, 30: 1345-1365. PMID: 30004848, PMCID: PMC6211568, DOI: 10.1162/jocn_a_01308.Peer-Reviewed Original ResearchAttending to What and Where: Background Connectivity Integrates Categorical and Spatial Attention
Tompary A, Al-Aidroos N, Turk-Browne NB. Attending to What and Where: Background Connectivity Integrates Categorical and Spatial Attention. Journal Of Cognitive Neuroscience 2018, 30: 1281-1297. PMID: 29791296, PMCID: PMC6570400, DOI: 10.1162/jocn_a_01284.Peer-Reviewed Original ResearchConceptsAttentional modulationSpatial attentionRetinotopic areasVisual areasGoal-relevant informationCategory-selective regionsVentral temporal cortexVisual cortexEarly visual cortexCategory-selective areasPattern of resultsAttentional goalsFeatural componentsAttentional componentsNeural basisBackground connectivityBehavioral goalsFrontoparietal areasSpatial selectionFunctional connectivityTemporal cortexSelective regionsExploratory analysisMost researchCortexNeural Overlap in Item Representations Across Episodes Impairs Context Memory
Kim G, Norman KA, Turk-Browne NB. Neural Overlap in Item Representations Across Episodes Impairs Context Memory. Cerebral Cortex 2018, 29: 2682-2693. PMID: 29897407, PMCID: PMC6519698, DOI: 10.1093/cercor/bhy137.Peer-Reviewed Original ResearchConceptsSubsequent source memorySource memoryContext memoryInitial contextBetter source memoryNovel contextual informationLateral occipital cortexNeural overlapRepresentational similarityNeural representationNeural patternsFMRI studyItem representationsSecond presentationLater retrievalDifferent tasksMemorySame itemsOccipital cortexInitial taskPattern similaritySuch reactivationInitial itemsNovel experienceContextual informationInfant fMRI: A Model System for Cognitive Neuroscience
Ellis CT, Turk-Browne NB. Infant fMRI: A Model System for Cognitive Neuroscience. Trends In Cognitive Sciences 2018, 22: 375-387. PMID: 29487030, PMCID: PMC5911209, DOI: 10.1016/j.tics.2018.01.005.Peer-Reviewed Original Research