2023
SDPS-20 THE HER2 FLIP: HER2 AMPLIFICATION OF TUMOR CELLS IN THE CEREBROSPINAL FLUID (CSF-TCS) OF PATIENTS WITH LEPTOMENINGEAL METASTASIS HAVING SOLID TUMORS; IMPLICATIONS FOR TREATING THE LM TUMOR WITH ANTI-HER2 THERAPY
Kumthekar P, Youssef M, Blondin N, Azadi A, Piccioni D, Glantz M, Carillo J, Avgeropoulos N, Makar S, Blouw B, Natasha A, Fisher D, Huynh L, Peters J, Sweed N, Dugan M, Kesari S. SDPS-20 THE HER2 FLIP: HER2 AMPLIFICATION OF TUMOR CELLS IN THE CEREBROSPINAL FLUID (CSF-TCS) OF PATIENTS WITH LEPTOMENINGEAL METASTASIS HAVING SOLID TUMORS; IMPLICATIONS FOR TREATING THE LM TUMOR WITH ANTI-HER2 THERAPY. Neuro-Oncology Advances 2023, 5: iii20-iii20. PMCID: PMC10402348, DOI: 10.1093/noajnl/vdad070.077.Peer-Reviewed Original ResearchNon-small cell lung cancerUpper GI cancerHER2-negative primary tumorsAnti-HER2 therapyBreast cancer patientsLeptomeningeal metastasesNegative primary tumorsPrimary tumorHER2 amplificationGI cancersCancer patientsNSCLC patientsBreast cancerHER2-positive primary tumorsUpper GI cancer patientsCSF tumor cellsGI cancer patientsPositive primary tumorsCell lung cancerDiscretion of physiciansIT trastuzumabLM tumorsHER2 positivityNSCLC cancerLM patients
2022
BIOM-05. THE HER2 FLIP: HER2 AMPLIFICATION OF TUMOR CELLS IN THE CEREBROSPINAL FLUID (CSF-TCS) OF PATIENTS WITH SOLID TUMOR LEPTOMENINGEAL METASTASIS
Kumthekar P, Youssef M, Blondin N, Azadi A, Piccioni D, Glantz M, Carillo J, Sharma A, Avgeropoulos N, Makar S, Blouw B, Natasha A, Fisher D, Huynh L, Peters J, Matsutani M, Sales E, Sweed N, Dugan M, Kesari S. BIOM-05. THE HER2 FLIP: HER2 AMPLIFICATION OF TUMOR CELLS IN THE CEREBROSPINAL FLUID (CSF-TCS) OF PATIENTS WITH SOLID TUMOR LEPTOMENINGEAL METASTASIS. Neuro-Oncology 2022, 24: vii4-vii5. DOI: 10.1093/neuonc/noac209.015.Peer-Reviewed Original ResearchNon-small cell lung cancerUpper GI cancerLeptomeningeal metastasesHER2 amplificationPrimary tumorBreast cancerLM patientsGI cancersCancer patientsHER2-positive primary breast cancerHER2-positive primary tumorsSolid-tumor leptomeningeal metastasisUpper GI cancer patientsCSF tumor cellsGI cancer patientsPositive primary tumorsPrimary breast cancerBreast cancer patientsCell lung cancerIT trastuzumabLM tumorsNSCL cancerNSCLC patientsUpper GIClinical benefit