An E3 ubiquitin ligase, cullin‐4 regulates retinal differentiation in Drosophila eye
Tare M, Chimata AV, Gogia N, Narwal S, Deshpande P, Singh A. An E3 ubiquitin ligase, cullin‐4 regulates retinal differentiation in Drosophila eye. Genesis 2020, 58: e23395. PMID: 32990387, PMCID: PMC9277906, DOI: 10.1002/dvg.23395.Peer-Reviewed Original ResearchConceptsCUL-4E3 ubiquitin ligaseEye developmentCullin 4Morphogenetic furrowRetinal differentiationUbiquitin ligaseCell deathForward genetic screenDrosophila eye modelEarly eye developmentSpecific cell typesGenetic screenDrosophila eyeGenomic stabilityEye phenotypeProcess of differentiationProtein degradationNegative regulatorGene expressionDevelopmental defectsFunction backgroundCell cycleMolecular mechanismsCell types