Chapter 11 Role of AMP-activated protein kinase and sirtuins as antiaging proteins
Ramu M, Vishal S, Gogia N. Chapter 11 Role of AMP-activated protein kinase and sirtuins as antiaging proteins. 2022, 241-278. DOI: 10.1016/b978-0-323-90235-9.00015-x.ChaptersProtein kinaseAMP/ATP ratioDifferent cellular compartmentsCommon cellular targetActivity of AMPKFuel-sensing enzymeAge-associated disordersChapter 11 RoleSirtuin isoformsCellular compartmentsAge-related disordersSirtuin modulatorsSirtuin activityDifferent speciesAMPKCellular targetsAMPK pathwayContext of agingMitochondrial functionMitochondrial disordersPotential therapeutic targetATP ratioAge-related processesKinaseSIRT1