2015
Chinese herbal medicine for miscarriage affects decidual micro-environment and fetal growth
Piao L, Chen C, Yeh C, Basar M, Masch R, Cheng Y, Lockwood CJ, Schatz F, Huang SJ. Chinese herbal medicine for miscarriage affects decidual micro-environment and fetal growth. Placenta 2015, 36: 559-566. PMID: 25771406, PMCID: PMC4395550, DOI: 10.1016/j.placenta.2015.02.006.Peer-Reviewed Original ResearchConceptsFirst trimester decidual cellsIL-1βDecidual cellsPlacental weightFetal growthFood intakeResorption rateFetal resorption rateM-CSFMaternal food intakeC motif ligand 2Intrauterine growth restrictionIGF-IR expressionInducible protein-10Anti-CD163 antibodyQRT-PCRChinese herbal formulaIL-8 productionChinese herbal medicineG-CSF expressionEndothelial cell angiogenesisPlacental IGFDecidual macrophagesFetal weightCytokine expression
2008
Preeclampsia-Related Inflammatory Cytokines Regulate Interleukin-6 Expression in Human Decidual Cells
Lockwood CJ, Yen CF, Basar M, Kayisli UA, Martel M, Buhimschi I, Buhimschi C, Huang SJ, Krikun G, Schatz F. Preeclampsia-Related Inflammatory Cytokines Regulate Interleukin-6 Expression in Human Decidual Cells. American Journal Of Pathology 2008, 172: 1571-1579. PMID: 18467705, PMCID: PMC2408417, DOI: 10.2353/ajpath.2008.070629.Peer-Reviewed Original ResearchConceptsIL-6 levelsIL-6Decidual cellsGestational age-matched control placentasElevated IL-6 levelsIL-6 mRNA levelsCommon pregnancy disorderGenesis of preeclampsiaUteroplacental blood flowFetal-placental unitInterleukin-6 levelsPathogenesis of preeclampsiaPro-inflammatory cytokinesEndothelial cell dysfunctionInterleukin-6 expressionHuman decidual cellsReal-time quantitative RT-PCRTime quantitative RT-PCRQuantitative RT-PCRFetal morbidityDecidual macrophagesPreeclamptic womenSystemic inflammationPregnancy disordersControl placentas