2023
Maximum Dose Rate of Intrapartum Oxytocin Infusion and Associated Obstetric and Perinatal Outcomes
Son M, Roy A, Grobman W, Miller E, Dude A, Peaceman A, Stetson B. Maximum Dose Rate of Intrapartum Oxytocin Infusion and Associated Obstetric and Perinatal Outcomes. Obstetrics And Gynecology 2023, 141: 379-386. PMID: 36649339, DOI: 10.1097/aog.0000000000005058.Peer-Reviewed Original ResearchMeSH KeywordsCesarean SectionDelivery, ObstetricDouble-Blind MethodFemaleHumansInfant, NewbornLabor, InducedOxytocicsOxytocinPregnancyConceptsTitration regimenCesarean deliveryVaginal deliveryMultivariable analysisAdverse outcomesNeonatal intensive care unit admissionComposite severe neonatal morbidityIntensive care unit admissionSecondary analysisCumulative proportionPerinatal adverse outcomesCare unit admissionSevere neonatal morbiditySpontaneous vaginal deliveryMagnesium sulfate infusionUnderwent cesarean deliveryRupture of membranesWeeks of gestationNICU admissionUnit admissionHypertensive disordersLack of evidenceNeonatal morbidityNulliparous patientsPerinatal outcomes
2021
High-Dose Compared With Standard-Dose Oxytocin Regimens to Augment Labor in Nulliparous Women
Son M, Roy A, Stetson BT, Grady NT, Vanecko MC, Bond N, Swanson K, Grobman WA, Miller ES, Peaceman AM. High-Dose Compared With Standard-Dose Oxytocin Regimens to Augment Labor in Nulliparous Women. Obstetrics And Gynecology 2021, 137: 991-998. PMID: 33957657, DOI: 10.1097/aog.0000000000004399.Peer-Reviewed Original ResearchConceptsHigh-dose groupHigh-dose oxytocin regimenStandard dosingAugmentation of laborUmbilical artery acidemiaLabor durationPrimary outcomeSecondary outcomesNulliparous womenCesarean birthNeonatal intensive care unit admissionIntensive care unit admissionApgar score 3Care unit admissionStandard-dose groupPrespecified secondary outcomesPrimary cesarean birthWeeks of gestationAugment laborClinical chorioamnionitisMorbidity compositeNulliparous participantsUnit admissionObstetric morbidityPerinatal outcomes