Featured Publications
Bleeding avoidance strategies and percutaneous coronary intervention outcomes: A 10-year observation from a Japanese Multicenter Registry
Sawano M, Spertus J, Masoudi F, Rumsfeld J, Numasawa Y, Inohara T, Kennedy K, Ueda I, Miyata H, Fukuda K, Kohsaka S. Bleeding avoidance strategies and percutaneous coronary intervention outcomes: A 10-year observation from a Japanese Multicenter Registry. American Heart Journal 2021, 235: 113-124. PMID: 33472053, DOI: 10.1016/j.ahj.2021.01.010.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionTransfemoral approachTransradial approachNational Cardiovascular Data Registry CathPCI RegistryVascular closure device usePercutaneous coronary intervention outcomesMultivariable logistic regression analysisClosure device useConsecutive PCI patientsJapanese multicenter registryAdjusted odds ratioLogistic regression analysisPCI patientsCathPCI RegistryCoronary interventionMulticenter registryBleeding rateJapanese patientsOdds ratioRisk scoreLower riskPatientsUS populationCathPCIJapanese population
2024
A Novel Risk Score for Major Bleeding in Japanese Patients with Non-Valvular Atrial Fibrillation: The J-RISK AF Study
Akao M, Tomita H, Nakai M, Kodani E, Suzuki S, Hayashi K, Sawano M, Goya M, Yamashita T, Fukuda K, Tsuda T, Isobe M, Toyoda K, Miyamoto Y, Okamura T, Sasahara Y, Okumura K, Group O. A Novel Risk Score for Major Bleeding in Japanese Patients with Non-Valvular Atrial Fibrillation: The J-RISK AF Study. Journal Of Atherosclerosis And Thrombosis 2024, 31: 1591-1606. PMID: 38811233, PMCID: PMC11537787, DOI: 10.5551/jat.64842.Peer-Reviewed Original ResearchNon-valvular atrial fibrillationOral anticoagulantsRisk stratification systemJapanese patientsHAS-BLEDAtrial fibrillationNon-valvular atrial fibrillation patientsMultivariate Cox proportional hazards analysisConcomitant antiplatelet agentsAF studyCox proportional hazards analysisRisk scoreStratification systemBleeding risk stratificationFollow-up periodNovel risk scoreProportional hazards analysisRisk of ischemic strokeAF RegistryNon-valvularBleeding historyMajor bleedingRisk stratificationAntiplatelet agentsBleeding
2023
Genetic Backgrounds Associated With Stent Thrombosis A Pilot Study From a Percutaneous Coronary Intervention Registry
Shoji S, Sawano M, Inohara T, Hiraide T, Ueda I, Suzuki M, Noma S, Fukuda K, Kohsaka S. Genetic Backgrounds Associated With Stent Thrombosis A Pilot Study From a Percutaneous Coronary Intervention Registry. JACC Advances 2023, 2: 100172. PMID: 38939036, PMCID: PMC11198226, DOI: 10.1016/j.jacadv.2022.100172.Peer-Reviewed Original ResearchEarly stent thrombosisLST/VLSTPercutaneous coronary interventionStent thrombosisPolygenic risk scoresCoronary interventionMulticenter PCI registryLate stent thrombosisA Pilot StudyDifferent genetic predispositionPCI patientsPCI registrySignificant single nucleotide polymorphismsPathophysiologic characteristicsPatient populationFatal eventsRisk scoreGenetic predispositionVLSTThrombosisPatientsPilot studyRegistryRisk predictionSingle nucleotide polymorphisms
2022
Machine learning models for prediction of adverse events after percutaneous coronary intervention
Niimi N, Shiraishi Y, Sawano M, Ikemura N, Inohara T, Ueda I, Fukuda K, Kohsaka S. Machine learning models for prediction of adverse events after percutaneous coronary intervention. Scientific Reports 2022, 12: 6262. PMID: 35428765, PMCID: PMC9012739, DOI: 10.1038/s41598-022-10346-1.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAdverse eventsRisk scoreHospital mortalityCoronary interventionConsecutive coronary artery disease patientsCoronary artery disease patientsAdverse periprocedural eventsLow-risk patientsMajor adverse eventsGood discriminationMulticenter registryPeriprocedural eventsDisease patientsClinical decisionLogistic regressionSpecific interventionsRisk predictionOverall risk predictionPatientsScoresInterventionMortalityAdequate discriminationOutcomes
2021
Evidence‐to‐Practice Gap for Preventing Procedure‐Related Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention
Shoji S, Sawano M, Sandhu A, Heidenreich P, Shiraishi Y, Noma S, Suzuki M, Numasawa Y, Fukuda K, Kohsaka S. Evidence‐to‐Practice Gap for Preventing Procedure‐Related Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention. Journal Of The American Heart Association 2021, 10: e020047. PMID: 34310187, PMCID: PMC8475676, DOI: 10.1161/jaha.120.020047.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overClinical Decision-MakingContrast MediaDatabases, FactualEvidence-Based MedicineFemaleHumansIncidenceJapanKidneyKidney Function TestsMaleMiddle AgedPercutaneous Coronary InterventionProfessional Practice GapsProtective FactorsQuality ImprovementQuality Indicators, Health CareRadiography, InterventionalRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeConceptsAcute kidney injuryPercutaneous coronary interventionAKI risk scoreBaseline renal functionContrast volumeCoronary interventionRisk scoreAKI riskKidney injuryRenal functionAcute coronary syndrome presentationBackground Acute kidney injuryIntra-aortic balloon pumpMultivariable linear regression analysisContrast volume usagePreprocedural risk assessmentChronic kidney diseaseAvailable risk scoresCommon complicationBalloon pumpHeart failureSusceptible patientsOverall incidenceSyndrome presentationKidney disease
2020
Association between bleeding avoidance and outcomes: Japanese coronary intervention registry report in collaboration with ACC-NCDR
Sawano M, Numasawa Y, Spertus J, Kennedy K, Inohara T, Miyata H, Fukuda K, Rumsfeld J, Masoudi F, Kohsaka S. Association between bleeding avoidance and outcomes: Japanese coronary intervention registry report in collaboration with ACC-NCDR. European Heart Journal 2020, 41: ehaa946.2512. DOI: 10.1093/ehjci/ehaa946.2512.Peer-Reviewed Original ResearchRadial accessBleeding rateJapanese patientsBAS useRisk scoreNational Cardiovascular Data Registry CathPCIClosure device useConsecutive Japanese patientsMultivariable logistic modelVascular closure deviceQuality improvement initiativesHigh-quality careFemoral accessRegistry reportsElective casesClosure deviceStudy populationAmerican CollegeEmergent casesACC-NCDRCathPCIQuality careAccess useObserved bleedingStudy periodExploring Triaging and Short-Term Outcomes of Early Invasive Strategy in Non-ST Segment Elevation Acute Coronary Syndrome: A Report from Japanese Multicenter Registry
Ikemura N, Shiraishi Y, Sawano M, Ueda I, Numasawa Y, Noma S, Suzuki M, Momiyama Y, Hayashida K, Yuasa S, Miyata H, Fukuda K, Kohsaka S. Exploring Triaging and Short-Term Outcomes of Early Invasive Strategy in Non-ST Segment Elevation Acute Coronary Syndrome: A Report from Japanese Multicenter Registry. Journal Of Clinical Medicine 2020, 9: 1106. PMID: 32294905, PMCID: PMC7230808, DOI: 10.3390/jcm9041106.Peer-Reviewed Original ResearchElevation acute coronary syndromeAcute kidney injuryAcute coronary syndromeHospital mortalityCoronary syndromeMortality riskRisk scoreNon-ST segment elevation acute coronary syndromesNon-ST elevation acute coronary syndromeSegment elevation acute coronary syndromesMultivariable logistic regression analysisJapanese multicenter registryMulticenter Japanese registryEarly invasive strategyChronic kidney diseasePeripheral artery diseaseHospital mortality riskPercutaneous coronary interventionShort-term outcomesRisk-benefit profileLower mortality riskLogistic regression analysisNSTE-ACSKidney injuryMulticenter registry
2019
Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure
Shoji S, Shiraishi Y, Sawano M, Katsumata Y, Yuasa S, Kohno T, Fukuda K, Spertus J, Kohsaka S. Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure. Heart And Vessels 2019, 34: 1464-1470. PMID: 30887105, DOI: 10.1007/s00380-019-01378-1.Peer-Reviewed Original ResearchConceptsClinical risk scorePatient-reported qualityLong-term prognosisHeart failureHHF patientsRisk scoreComposite outcomeAcute settingGWTG-HF risk scoreHospitalized HF patientsAcute heart failureChronic heart failurePrimary therapeutic targetHealth care providersFirst yearCause mortalityHF patientsHF readmissionPatient characteristicsIndependent predictorsAcute phasePrognostic indicatorJapanese patientsPrognostic assessmentCare providers
2017
PERFORMANCE OF THE MAGGIC HEART FAILURE RISK SCORE IN JAPANESE ACUTE HEART FAILURE PATIENTS: A REPORT FROM THE WEST TOKYO HEART FAILURE REGISTRY
Sawano M, Inohara T, Shiraishi Y, Kohsaka S, Kohno T, Goda A, Mizuno A, Sujino Y, Nagatomo Y, Mahara K, Fukuda K, Yoshikawa T. PERFORMANCE OF THE MAGGIC HEART FAILURE RISK SCORE IN JAPANESE ACUTE HEART FAILURE PATIENTS: A REPORT FROM THE WEST TOKYO HEART FAILURE REGISTRY. Journal Of The American College Of Cardiology 2017, 69: 947. DOI: 10.1016/s0735-1097(17)34336-x.Peer-Reviewed Original Research
2016
Independent Prognostic Value of Single and Multiple Non-Specific 12-Lead Electrocardiographic Findings for Long-Term Cardiovascular Outcomes: A Prospective Cohort Study
Sawano M, Kohsaka S, Okamura T, Inohara T, Sugiyama D, Shiraishi Y, Watanabe M, Nakamura Y, Higashiyama A, Kadota A, Okuda N, Murakami Y, Ohkubo T, Fujiyoshi A, Miura K, Okayama A, Ueshima H, . Independent Prognostic Value of Single and Multiple Non-Specific 12-Lead Electrocardiographic Findings for Long-Term Cardiovascular Outcomes: A Prospective Cohort Study. PLOS ONE 2016, 11: e0157563. PMID: 27362562, PMCID: PMC4928789, DOI: 10.1371/journal.pone.0157563.Peer-Reviewed Original ResearchConceptsFramingham risk scoreCardiovascular deathRisk chartsRisk scoreCohort studyLong-term cardiovascular deathLong-term prognostic effectLong-term cardiovascular outcomesProspective cohort studyIndependent prognostic valueLongitudinal cohort studyRisk stratification systemCause deathCardiovascular outcomesCoronary deathElectrocardiogram findingsHazard ratioPrognostic impactStroke deathsElectrocardiographic findingsPrognostic effectPrognostic valueHealthy menRepolarization abnormalitiesHigh risk
2015
Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level
Shiraishi Y, Kohsaka S, Abe T, Mizuno A, Goda A, Izumi Y, Yagawa M, Akita K, Sawano M, Inohara T, Takei M, Kohno T, Higuchi S, Yamazoe M, Mahara K, Fukuda K, Yoshikawa T, Investigators W. Validation of the Get With The Guideline–Heart Failure risk score in Japanese patients and the potential improvement of its discrimination ability by the inclusion of B-type natriuretic peptide level. American Heart Journal 2015, 171: 33-39. PMID: 26699598, DOI: 10.1016/j.ahj.2015.10.008.Peer-Reviewed Original ResearchConceptsB-type natriuretic peptide levelsGWTG-HF risk scoreAcute heart failureNatriuretic peptide levelsHospital mortalityRisk scorePeptide levelsAHF patientsC-statisticGuidelines-Heart Failure (GWTG-HF) risk scoreWest Tokyo Heart Failure registryChronic obstructive pulmonary diseaseBlood urea nitrogen levelsGWTG-HF scoreHeart Failure RegistryMulticenter cohort registryRisk score performanceObstructive pulmonary diseaseSystolic blood pressureUrea nitrogen levelsHosmer-Lemeshow statisticFuture risk modelsCohort registryBlood pressureHeart failure