2024
Tumor response assessment in hepatocellular carcinoma treated with immunotherapy: imaging biomarkers for clinical decision-making
Sobirey R, Matuschewski N, Gross M, Lin M, Kao T, Kasolowsky V, Strazzabosco M, Stein S, Savic L, Gebauer B, Jaffe A, Duncan J, Madoff D, Chapiro J. Tumor response assessment in hepatocellular carcinoma treated with immunotherapy: imaging biomarkers for clinical decision-making. European Radiology 2024, 1-11. PMID: 39033181, DOI: 10.1007/s00330-024-10955-6.Peer-Reviewed Original ResearchMedian overall survivalTumor response criteriaTumor response assessmentHepatocellular carcinoma patientsHepatocellular carcinomaTumor responseOverall survivalResponse criteriaResponse assessmentNon-respondersPoorer median overall survivalPrediction of tumor responsePredictive valueHepatocellular carcinoma immunotherapyDisease controlPrognostic of survivalClinical baseline parametersLog-rank testKaplan-Meier curvesMultivariate Cox regressionPredicting overall survivalCox regression modelsSurvival benefitStratify patientsMRI pre-
2022
Three-Dimensional Quantitative Tumor Response and Survival Analysis of Hepatocellular Carcinoma Patients Who Failed Initial Transarterial Chemoembolization: Repeat or Switch Treatment?
Zhao Y, Haroun R, Sahu S, Schernthaner R, Smolka S, Lin M, Hong K, Georgiades C, Duran R. Three-Dimensional Quantitative Tumor Response and Survival Analysis of Hepatocellular Carcinoma Patients Who Failed Initial Transarterial Chemoembolization: Repeat or Switch Treatment? Cancers 2022, 14: 3615. PMID: 35892874, PMCID: PMC9329887, DOI: 10.3390/cancers14153615.Peer-Reviewed Original ResearchOverall survivalSecond TACEHepatocellular carcinoma patientsFirst TACECarcinoma patientsTumor responseInitial transarterial chemoembolizationMedian overall survivalTransarterial chemoembolization sessionsKaplan-Meier methodLonger overall survivalLog-rank testChemoembolization sessionsConsecutive patientsTransarterial chemoembolizationSurvival outcomesHCC patientsTreatment responseTumor enhancementPatientsSurvival analysisTACEEuropean AssociationRespondersSignificant differences
2016
3:36 PMAbstract No. 53 Which response criteria can predict early tumor response in CT image in hepatocellular carcinoma patients treated with TACE: RECIST, mRECIST, EASL or qEASL?
Zhao Y, Sahu S, Bai W, Schernthaner R, Duran R, Chapiro J, Yin Z, Lin M, Han G, Geschwind J. 3:36 PMAbstract No. 53 Which response criteria can predict early tumor response in CT image in hepatocellular carcinoma patients treated with TACE: RECIST, mRECIST, EASL or qEASL? Journal Of Vascular And Interventional Radiology 2016, 27: s28. DOI: 10.1016/j.jvir.2015.12.084.Peer-Reviewed Original ResearchEarly tumor responseHepatocellular carcinoma patientsCarcinoma patientsTumor responseResponse criteriaCT imagesRECIST
2015
Radiologic-pathologic analysis of quantitative 3D tumour enhancement on contrast-enhanced MR imaging: a study of ROI placement
Chockalingam A, Duran R, Sohn JH, Schernthaner R, Chapiro J, Lee H, Sahu S, Nguyen S, Geschwind JF, Lin M. Radiologic-pathologic analysis of quantitative 3D tumour enhancement on contrast-enhanced MR imaging: a study of ROI placement. European Radiology 2015, 26: 103-113. PMID: 25994198, PMCID: PMC4654989, DOI: 10.1007/s00330-015-3812-2.Peer-Reviewed Original ResearchConceptsTranscatheter arterial chemoembolizationHCC patientsIpsilateral placementTumor enhancementHepatocellular carcinoma patientsROI placementContrast-enhanced MR imagingRadiologic-pathologic analysisArterial chemoembolizationCarcinoma patientsPathological correlationIntra-class correlationPatientsMR imagingClinical methodsMedian differencePathologyInterest placementHistopathology4:42 PM, Abstract No. 55 Association of intra-procedural cone-beam CT use with overall survival in hepatocellular carcinoma patients treated with TACE
Sohn J, Lin M, Lee H, Sahu S, Schernthaner R, Duran R, Zhao Y, Fleckenstein F, Zhao L, Geschwind J. 4:42 PM, Abstract No. 55 Association of intra-procedural cone-beam CT use with overall survival in hepatocellular carcinoma patients treated with TACE. Journal Of Vascular And Interventional Radiology 2015, 26: s30. DOI: 10.1016/j.jvir.2014.12.087.Peer-Reviewed Original Research