Production, purification, and functional analysis of recombinant human and mouse 17β-hydroxysteroid dehydrogenase type 7
Törn S, Nokelainen P, Kurkela R, Pulkka A, Menjivar M, Ghosh S, Coca-Prados M, Peltoketo H, Isomaa V, Vihko P. Production, purification, and functional analysis of recombinant human and mouse 17β-hydroxysteroid dehydrogenase type 7. Biochemical And Biophysical Research Communications 2003, 305: 37-45. PMID: 12732193, DOI: 10.1016/s0006-291x(03)00694-6.Peer-Reviewed Original ResearchConceptsPeripheral tissuesType 7Primary open-angle glaucomaEarly-onset prostate cancerOpen-angle glaucomaSex steroid hormonesIntracrine regulatorAdrenal glandProstate cancerEstrogenic milieuPotent androgenInactive metabolitesEstrogenic metabolitesSteroid metabolismPotent estrogenSteroid hormonesCancer 1DihydrotestosteroneRecombinant humanTissue distributionHormoneTissueHuman tissuesPresent studyMetabolic role