1996
Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro
Escribano J, Alonso G, Coca-Prados M, Fernández J. Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro. Cancer Letters 1996, 100: 23-30. PMID: 8620447, DOI: 10.1016/0304-3835(95)04067-6.Peer-Reviewed Original ResearchConceptsExtract of saffronCytotoxic effectsCell growth inhibitionCancer therapeutic agentsHuman tumor cellsHuman cancer cellsPyknotic nucleiInhibitory growth effectTherapeutic agentsTumor cellsCancer cellsEthanolic extractApoptosis inductionCrocinGrowth inhibitionReduced cytoplasmCell growthCellsCrocetinCell shrinkageDosesHeLa cells
1986
Growth of non-pigmented ciliary epithelial cells in serum-free hormone-supplemented media
Coca-Prados M, Chatt G. Growth of non-pigmented ciliary epithelial cells in serum-free hormone-supplemented media. Experimental Eye Research 1986, 43: 617-629. PMID: 3792464, DOI: 10.1016/s0014-4835(86)80028-8.Peer-Reviewed Original ResearchConceptsNPE cellsClathrin-coated vesiclesCiliary epithelial cellsNerve growth factorEpithelial cellsNon-pigmented ciliary epithelial cellsCellular polarityGrowth factorCellular junctionsPrimary culturesCoated pitsArtificial substratesTransport activityCulture mediumMicrofilament bundlesCell growthSerum-free hormone-supplemented mediumJunctional complexesIntermediate filamentsCell proliferationAdjacent cellsCellsSerum-free culture medium