2023
A Mouse Model of MHV‐1 Virus Infection for Study of Acute and Long COVID Infection
Masciarella A, Di Gregorio D, Ramamoorthy R, Hussain H, Jayakumar A, Paidas M. A Mouse Model of MHV‐1 Virus Infection for Study of Acute and Long COVID Infection. Current Protocols 2023, 3: e896. PMID: 37867460, PMCID: PMC10606938, DOI: 10.1002/cpz1.896.Peer-Reviewed Original ResearchConceptsSARS-CoV-2Pathological changesMouse modelTransgenic miceLong-term organ dysfunctionSARS-CoV-2 pathophysiologyIrreversible neurological complicationsPotential therapeutic interventionsAvailable human dataBiosafety level 2 laboratoryNon-human primatesBiosafety level 3 laboratoryNeurological complicationsOrgan dysfunctionAcute stageClinical symptomsLong-term effectsSevere casesClinical observationsViral infectionTherapeutic interventionsMHV-1Animal preparationsWeight lossBSL-3 laboratory
2009
Involvement of human decidual cell-expressed tissue factor in uterine hemostasis and abruption
Lockwood C, Paidas M, Murk W, Kayisli U, Gopinath A, Huang S, Krikun G, Schatz F. Involvement of human decidual cell-expressed tissue factor in uterine hemostasis and abruption. Thrombosis Research 2009, 124: 516-520. PMID: 19720393, PMCID: PMC2787516, DOI: 10.1016/j.thromres.2009.07.017.Peer-Reviewed Original ResearchConceptsDecidual cellsTissue factorPlacental ischemiaTF expressionDecidual cell-expressed tissue factorCultured term decidual cellsAutocrine/paracrine fashionDecidual spiral arteriesDecidual vascular remodelingTerm decidual cellsUteroplacental blood flowMaternal-fetal interfaceAutocrine/paracrine mediatorsDecidual infiltrationHemostatic protectionUterine hemostasisDecidual hemorrhageExtracellular matrixSpiral arteriesFetal interfaceHuman pregnancyVascular injuryConductance vesselsSFlt-1Interleukin-8